Results 81 to 90 of about 70,792 (305)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Chemophenetic investigation of epicuticular n-alkanes in Juniperus L. section Juniperus L. from the Balkans [PDF]

open access: yesBotanica Serbica
Junipers are one of the most diverse groups of gymnosperms today. They are adapted to arid areas of the world. In this study, we analysed the chemical composition of the leaf n-alkanes of 170 individuals belonging to Juniperus communis subsp. communis,
Nemanja Rajčević   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The cuticle micromorphology of extant and fossil plants as indicator of environmental conditions. A pioneer study on the influence of volcanic gases on the cuticle structure in extant plants

open access: yes, 2011
The leaves of many tracheophytes are covered with a cuticle, an extracellular membrane covering aerial organs of plants. The gas exchanges between the plant and the surrounding atmosphere are mediated by the cuticle; its acts as the main barrier to air ...
Bartiromo, Antonello
core  

Microscopy of crustacean cuticle

open access: yes, 2019
Structural and functional properties of exoskeleton in moulting sea slaters Ligia pallasii from the Eastern Pacific coast were investigated with CT scanning and electron microscopy.
Blejec, Andrej   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Natural variation of wheat cuticular waxes in relation to drought tolerance

open access: yesФактори експериментальної еволюції організмів, 2015
Aims. The aim of our research is to investigate the role of wheat leaf cuticle in drought and heat protection by characterizing natural variability of cuticle components and revealing genetic and biochemical background of this variability in Australian ...
H. Bi   +6 more
doaj  

Cuticles of Erupted Teeth [PDF]

open access: yesNature, 1954
IT is generally agreed that Nasmyth's membrane, which is present on the enamel surface of recently erupted teeth, is composed of an outer cellular and an inner structureless layer, and that shortly after eruption the cells are lost due to degeneration and masticatory trauma.
openaire   +2 more sources

Oviposition time, interval and cuticle deposition

open access: yes
1) The cuticle acts as a barrier to prevent microbial penetration of the eggshell. The reduction in the oviposition interval with selection for egg production and the activity of clock genes in the oviduct led to testing the hypothesis that the interval ...
Struthers, Sarah   +6 more
core   +1 more source

Ultrastructure of the cuticle of chalimus larva of the salmon louse Lepeophtheirus salmonis (Kroyer, 1837) (Copepoda, Caligidae) [PDF]

open access: yes, 2000
The cuticle of the chalimus II stage of Lepeophtheirus salmonis (Copepoda: Caligidae) comprised a four-layered epicuticle with a pronounced fuzzy coat which was separated from the outer and inner procuticles by a layer of transitional procuticle.
Shinn, A.P.   +5 more
core  

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