Results 41 to 50 of about 809,107 (265)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
World Journal of Nuclear Medicine, 2018 The use of F-18 sodium fluoride (NaF) positron emission tomography/computed tomography (PET/CT) bone scan is increasing because of its higher sensitivity and specificity over standard bone scintigraphy (BS).
Ismet Sarikaya +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Cancer Management and Research, 2020 Jie Chen,1 Jingwen Luo,2 Xia He,3 Chenjing Zhu3 1Department of Oncology, Xuzhou Medical University, Xuzhou, Jiangsu, People’s Republic of China; 2Department of Oncology, West China School of Medicine, West China Hospital, Sichuan University ...
Chen J, Luo J, He X, Zhu C
doaj
Determination of Susceptibility Breakpoint for Cefquinome against Streptococcus suis in Pigs
Antibiotics, 2021 Streptococcus suis (S. suis), a zoonotic pathogen, causes severe diseases in both pigs and human beings. Cefquinome can display excellent antibacterial activity against gram-negative and gram-positive bacteria.
Kun Mi +9 more
doaj +1 more source
, 2023 We study the simple random walk on trees and give estimates on the mixing and relaxation times. Relying on a seminal result by Basu, Hermon and Peres characterizing cutoff on trees, we give geometric criteria that are easy to verify and allow to ...
Gantert, Nina;Nestoridi, Evita;Schmid, Dominik +7 more
core +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Universality in protein residue networks [PDF]
, 2010 Residue networks representing 595 nonhomologous proteins are studied. These networks exhibit universal topological characteristics as they belong to the topological class of modular networks formed by several highly interconnected clusters separated by ...
Estrada, Ernesto +3 more
core +3 more sources
Point of care assessment of cardiac troponin T level in CKD patients with chest symptom
Renal Failure, 2017 We challenged to identify the cutoff value of cTnT in chronic kidney disease (CKD) patients by point of care assessment way. A single center, prospective cross-sectional study was planned and performed. 201 consecutive patients who were visited emergency
Masaki Iwasaki +8 more
doaj +1 more source