Results 101 to 110 of about 254,674 (333)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Numerical Simulation on Cutting and Breaking of Heterogeneous Conglomerate by Special-Shaped PDC Cutter

Shiyou jixie
When the PDC bit is used to drill conglomerate formations， the frequent impact loads reduce the expected life of PDC cutter， leading to frequent bit changes and ultimately affecting drilling efficiency.
Shi Jiangang, Li Gensheng, Liu Weiji, Wu Desheng, Zhang Nan, Deng Kaichuang   +5 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Numerical Analysis of the Influence of PDC Cutting Edge Radius on Temperature Distribution

Shiyou jixie, 2020
The temperature generated during the rock cutting process is the important factors that affect the cutting efficiency and service life of the cutter. The temperature distribution model of the interaction between the arc cutter and the rock is established.
Zheng Guojing, Zhou Qin, Zhang Kai, Zhang Zaixing   +3 more
doaj  

PENGARUH KONDISI CAIRAN PENDINGIN TERHADAP KEAUSAN CUTTER END MILL HSS PADA PROSES PEMESINAN BAJA KARBON SEDANG [PDF]

, 2014
Gesekan yang dialami cutter end mill oleh permukaan geram yang mengalir dan permukaan benda kerja yang telah terpotong pada saat proses pemesinan berlangsung mengakibatkan keausan cutter end mill .
rifqi fadli azhar hasibuan
core  

Low-cost Fabrication of PDMS Microfluidic Chamber using Digital Cutter Machine

, 2021
Isa Anshori, Suksmandhira Harimurti, Michelle Hartono, Raih Rona Althof, Lavita Nuraviana Rizalputri, Murni Handayani, Tati Latifah Mengko, Brian Yuliarto   +7 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Improvement of Image Alignment Using Camera Attitude Information [PDF]

, 2001
We discuss a proposed technique for incorporation of information from a variety of sensors in a video imagery processing pipeline. The auxiliary information allows one to simplify computations, effectively reducing the number of independent parameters in
Cutter, Randy G, Jr., Huff, Lloyd C, Rzhanov, Yuri   +2 more
core   +2 more sources