Results 81 to 90 of about 243,051 (307)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Making of wing models by tangent-milling [PDF]

open access: yes, 1971
Wings whose surfaces arc developable have been milled on a jig-borer at the National Aeronautical Laboratory, Bangalore, employing tangential milling. In this process, the Wing cross-section is approximated by a polygon which can be smoothened by hand ...
Jarandhan, S, Sankar, R
core  

The impact of tool selection on back and wrist injury risk in tying steel reinforcement bars: a single case experiment [PDF]

open access: yes, 2019
The paper explores the risk of work-related musculoskeletal injury in tying steel reinforcement bars. Three tools are compared to determine the extent to which ergonomic tools can reduce the risk of injury to the back and wrist in steel-tying.
Fitzgerald, Chris   +4 more
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Research on Cutting Load and Heat Generation Law of PDC Wearing Cutter

open access: yesShiyou jixie, 2021
At present, there is no further researches on the cutting load and heat generation of worn PDC cutter under different front rake angles and different wear grades. For this reason, single cutter cutting tests are used to verify the relevant performance of
Zhu Guanghui, Kuang Yuchun, Lin Wei
doaj  

On The Content and Character of Pain Experience [PDF]

open access: yes, 2019
Tracking representationalism explains the negative affective character of pain, and its capacity to motivate action, by reference to the representation of the badness for us of bodily damage.
Gray, Richard
core   +3 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Analysis and Enlightenment on the Relationships between Two Kinds of Cutter Life Evaluation Indexes and Installation Radius: A Case Study

open access: yesBuildings
Accurate evaluation of cutter life at different cutter positions on the cutter head is helpful to determine the time of cutter change and reduce the time of cutter wear measurement, which is of great significance to improve the tunneling efficiency of ...
Jianping Liu   +4 more
doaj   +1 more source

Phenolic cutter for machining foam insulation [PDF]

open access: yes, 1970
Pre-pregged fiber glass is an efficient abrasive for machining polystyrene and polyurethane foams. It bonds easily to any cutter base made of aluminum, steel, or phenolic, is inexpensive, and is readily ...
Blair, T. A.   +3 more
core   +1 more source

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