Results 71 to 80 of about 64,436 (298)
Shiyou jixieWhen the PDC bit is used to drill conglomerate formations， the frequent impact loads reduce the expected life of PDC cutter， leading to frequent bit changes and ultimately affecting drilling efficiency.
Shi Jiangang +5 more
doaj +3 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Predictive Methods for the Fire Resistance of Single Skin and Sandwich Composite Materials
, 2008 Polymer composite materials are becoming increasingly popular in many engineeringstructures in the civil, aerospace, marine and automotive industries. The increasedstrength and stiffness to weight ratios which are possible with certain types ofcomposites
Cutter, Philip Anthony
core +2 more sources
BuildingsAccurate evaluation of cutter life at different cutter positions on the cutter head is helpful to determine the time of cutter change and reduce the time of cutter wear measurement, which is of great significance to improve the tunneling efficiency of ...
Jianping Liu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Research on Cutting Load and Heat Generation Law of PDC Wearing Cutter
Shiyou jixie, 2021 At present, there is no further researches on the cutting load and heat generation of worn PDC cutter under different front rake angles and different wear grades. For this reason, single cutter cutting tests are used to verify the relevant performance of
Zhu Guanghui, Kuang Yuchun, Lin Wei
doaj
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source