Results 151 to 160 of about 1,349,956 (360)

INFLUENCE OF SELECTED CUTTING CONDITIONS ON CUTTING FORCES

Advances in Science and Technology Research Journal, 2017
Izabela Miturska, Ingrid Görögová, Augustín Görög, Maria Kapustova, Dana Stančeková   +4 more
openaire   +2 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

ANALYTICAL PARAMETERS DETERMINATION OF CUTTING POWER TENSION [PDF]

Fiabilitate şi Durabilitate, 2015
analytically identified components of the cutting force, cutting and conventional stress conditions reduction for blade and grinding. Substantiated conditions for transition from the cutting process to the process of plastic deformation of the material
Feodor NOVIKOV
doaj  

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Sufficient conditions for cut elimination with complexity analysis

Annals of Pure and Applied Logic, 2007
AbstractSufficient conditions for first-order-based sequent calculi to admit cut elimination by a Schütte–Tait style cut elimination proof are established. The worst case complexity of the cut elimination is analysed. The obtained upper bound is parameterized by a quantity related to the calculus.
openaire   +2 more sources

The Effect Of The Tool Geometry And Cutting Conditions On The Tool Deflection And Cutting Forces

, 2010
In this paper by measuring the cutting forces the effect of the tool shape and qualifications (sharp and worn cutting tools of both vee and knife edge profile) and cutting conditions (depth of cut and cutting speed) in the turning operation on the tool deflection and cutting force is investigated.
A. Fata, B. Nikuei
openaire   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Determination of stability of the cutting process under dynamic loading conditions

Технічна інженерія
An approach to quantitatively determining the stability of the cutting process under dynamic loading conditions is demonstrated. With this method, it is proposed to evaluate the time series of cutting force values and determine the stability index as a ...
A.S. Manokhin, S.An. Klimenko, S.A. Klimenko, M.Yu. Kopieikina, Yu.O. Melniychuk, A.O. Chumak, A.G. Naidenko   +6 more
doaj   +1 more source

Acoustic emission and vibration for tool wear monitoring in single-point [PDF]

, 2001
This paper proposes an implementation of calibrated acoustic emission (AE) and vibration techniques to monitor progressive stages of flank wear on carbide tool tips.
Au, YHJ, Jones, BE, Prateepasen, A
core  

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source