Results 51 to 60 of about 1,418,495 (362)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Evaluation of Cutting Forces and Temperatures in Micro-Milling of NiTi Alloys Using Finite Element Modeling

Журнал інженерних наук
Today, micro-milling of NiTi alloys is used to manufacture precision mechanisms, instrumentation, space technology, micro-electro-mechanical systems, biomedical devices, and implants. It is becoming increasingly widespread.
Nataliia Balytska, Oleh Tomashevskyi, Valentina Shadura   +2 more
doaj   +1 more source

Milling machinability analysis of GW63K rare-earth magnesium alloys based on the concept of clean cutting

Journal of Materials Research and Technology, 2023
GW63K rare-earth magnesium (Mg-RE) alloys have been widely used in various advanced industries for their excellent mechanical properties. However, the machinability of GW63K alloys under clean cutting conditions still needs to be better understood.
Jinyang Xu, Jiaxin Shen, Linfeng Li, Guoqiang Guo, Xinfa Zhu, Yi Meng, Ming Chen   +6 more
doaj   +1 more source

Machining stability and machine tool dynamics [PDF]

, 2007
Machining is a common manufacturing process in industry due to its high flexibility and ability to produce parts which excellent quality. The productivity and quality in machining operations can be limited by several process constraints one of which is ...
Budak, Erhan
core  

Investigation of a scale-up manufacturing approach for nanostructures by using a nanoscale multi-tip diamond tool [PDF]

, 2015
Increasing interest in commercializing functional nanostructured devices heightens the need for cost-effective manufacturing approaches for nanostructures.
Jiang, Xiangqian, Liang, Yingchun, Luo, Xichun, Sun, Jining, Tong, Zhen   +4 more
core   +1 more source

On conditional cuts for stochastic dual dynamic programming

EURO Journal on Computational Optimization, 2020
26 pages, 10 ...
W. van Ackooij, X. Warin
openaire   +3 more sources

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Surface roughness modeling of CBN hard steel turning [PDF]

, 2018
Study in the paper investigate the influence of the cutting conditions parameters on surface roughness parameters during turning of hard steel with cubic boron nitrite cutting tool insert. For the modeling of surface roughness parameters was used central
Ješić, D., Kovač, P., Nedic, B., Rodić, D., Savković, B., Taric, M.   +5 more
core  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Research on Conventional and High-Speed Machining Cutting Force of 7075-T6 Aluminum Alloy Based on Finite Element Modeling and Simulation

Metals, 2022
In current industrial practice, the finite element modeling of the metal cutting process is essential. In this paper, finite element analysis of conventional and high-speed cutting of 7075-T6 aluminum alloy is carried out.
Zhijie Wang, Yan Cao, Sergey Gorbachev, Victor Kuzin, Weiliang He, Junde Guo   +5 more
doaj   +1 more source