Results 71 to 80 of about 1,424,201 (360)

Surface microhardening studies on steels after high feed milling [PDF]

open access: yes, 2018
The paper deals with the impact of high-speed machining production methods on the integrity of component surfaces. One has to point out that cutting conditions during machining have a significant impact on the final properties of surface and subsurface ...
Petrů, Jana   +3 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

A Review of Insights and Research Progress on Hard Turning

open access: yesAnnals of "Dunarea de Jos" University of Galati, Fascicle XII, Welding Equipment and Technology
Of late, due to the launch of improved machine tool designs and extremely hard cutting tools, “Hard Turning” (HT) or “Hard Finish Turning” (HFT) has turned out to be an innovative, cost-effective, and smart alternative to the traditional grinding and ...
S. Girisankar   +2 more
doaj   +1 more source

In-Process Chatter Detection in Surface Grinding

open access: yesMATEC Web of Conferences, 2015
The chatter causes the poor surface finish during the surface grinding. It is therefore necessary to monitor the chatter during the process. Hence, this research has proposed the in-process chatter detection in the surface grinding process by utilizing ...
Tangjitsitcharoen Somkiat   +1 more
doaj   +1 more source

Investigation of a scale-up manufacturing approach for nanostructures by using a nanoscale multi-tip diamond tool [PDF]

open access: yes, 2015
Increasing interest in commercializing functional nanostructured devices heightens the need for cost-effective manufacturing approaches for nanostructures.
Jiang, Xiangqian   +4 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Cutting Force in Stone Machining by Diamond Disk

open access: yesAdvances in Materials Science and Engineering, 2010
Stone machining by diamond disk is a widespread process to manufacture standard products, such as tiles, slabs, and kerbs. Cutting force and energy may be used to monitor stone machining.
S. Turchetta
doaj   +1 more source

Effect of cutting conditions and tool geometry on process damping in machining [PDF]

open access: yes, 2011
Process damping can be a significant source of enhanced stability in metal cutting operations especially at low cutting speeds. However, it is usually ignored in stability analysis since models and methods on prediction and identification of process ...
Budak, Erhan   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Experimental Study on Surface Roughness and Flank Wear in Turning of Nimonic C263 under Dry Cutting Conditions [PDF]

open access: hybrid, 2021
J. Francis Xavier   +5 more
openalex   +1 more source

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