Results 81 to 90 of about 1,433,621 (312)

Machining stability and machine tool dynamics [PDF]

, 2007
Machining is a common manufacturing process in industry due to its high flexibility and ability to produce parts which excellent quality. The productivity and quality in machining operations can be limited by several process constraints one of which is ...
Budak, Erhan
core  

Simulation of the deflected cutting tool trajectory in complex surface milling [PDF]

, 2011
Since industry is rapidly developing, either locally or globally, manufacturers witness harder challenges due to the growing competitivity. This urges them to better consider the four factors linked to production and output: quality, quantity, cost and
Ali Zghal, E Budak, EM Lim, Gilles Dessein, GM Kim, KMY Law, M Milfelner, M Smaoui, MA Salgado, Maher Baili, MC Kang, Moez Smaoui, MW Cho, MW Cho, P Dépince, SH Suh, TI Seo, Z Lechniak, Zoubeir Bouaziz   +18 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cutting Force in Stone Machining by Diamond Disk

Advances in Materials Science and Engineering, 2010
Stone machining by diamond disk is a widespread process to manufacture standard products, such as tiles, slabs, and kerbs. Cutting force and energy may be used to monitor stone machining.
S. Turchetta
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A Pre-Study of the Relationship Between Machining Technology Parameters and Surface Roughness in the Scope of the Optimal Cost Efficiency of Machining

Engineering Proceedings
This research investigates the relationship between machining technology parameters and surface roughness to optimize the cost efficiency of machining processes.
László Pálfi, József Beke, Szabolcs Szalai   +2 more
doaj   +1 more source

Application of the stability lobes theory to milling of thin workpieces, experimental approach [PDF]

, 2003
The optimisation of cutting conditions in High Speed Machining (HSM) requires the use of a vibratory approach in order to avoid a fast deterioration of the tool and of the spindle, as well as a loss of quality of the surface rough- ness.
Arnaud, Lionel, Dessein, Gilles
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Wood Crosscutting Process Analysis for Circular Saws

BioResources, 2016
This article deals with the influence of some cutting parameters (geometry of cutting edge, wood species, and circular saw type) and cutting conditions on the wood crosscutting process carried out with circular saws.
Jozef Krilek, Ján Kováč, Marián Kučera   +2 more
doaj   +1 more source

Modelling of cutting process impact on machine tool thermal behaviour based on experimental data [PDF]

, 2017
Achieving high workpiece accuracy is a long-term goal of machine tool designers. There are many causes of workpiece inaccuracy, with thermal errors being the most dominant.
Horejš O., Mareš M.
core   +1 more source