Results 81 to 90 of about 1,418,495 (362)
On Measurement and Interpretation of Toughness Behaviour of Carbide Tools [PDF]
, 1981 The actual significance of any definition of toughness behaviour of carbide tools depends on the existence of an interrelation between the quality as defined and the occurrence of chipping and premature failure in cutting.
Kals, H.J.J.
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
In-Process Chatter Detection in Surface Grinding
MATEC Web of Conferences, 2015 The chatter causes the poor surface finish during the surface grinding. It is therefore necessary to monitor the chatter during the process. Hence, this research has proposed the in-process chatter detection in the surface grinding process by utilizing ...
Tangjitsitcharoen Somkiat +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Effect of cutting conditions and tool geometry on process damping in machining [PDF]
, 2011 Process damping can be a significant source of enhanced stability in metal cutting operations especially at low cutting speeds. However, it is usually ignored in stability analysis since models and methods on prediction and identification of process ...
Budak, Erhan +2 more
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Modelling and simulation of the dynamic cutting process and surface topography generation in nano/micro cutting [PDF]
, 2008 In nano/micro cutting process, the surface quality is heavily dependent on all the dynamic factors in machining including those from the material, tooling, cutting parameters, servo accuracy, mechanical structure deformation, and non-linear factors as ...
Cheng, K, Zhou, L
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Wood Crosscutting Process Analysis for Circular Saws
BioResources, 2016 This article deals with the influence of some cutting parameters (geometry of cutting edge, wood species, and circular saw type) and cutting conditions on the wood crosscutting process carried out with circular saws.
Jozef Krilek +2 more
doaj +1 more source
Analytical models for high performance milling. Part I: cutting forces, structural deformations and tolerance integrity [PDF]
, 2006 Milling is one of the most common manufacturing processes in industry. Despite recent advances in machining technology, productivity in milling is usually reduced due to the process limitations such as high cutting forces and stability.
Budak, Erhan
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