Results 81 to 90 of about 1,424,201 (360)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

A Pre-Study of the Relationship Between Machining Technology Parameters and Surface Roughness in the Scope of the Optimal Cost Efficiency of Machining

Engineering Proceedings
This research investigates the relationship between machining technology parameters and surface roughness to optimize the cost efficiency of machining processes.
László Pálfi, József Beke, Szabolcs Szalai   +2 more
doaj   +1 more source

A comparative study of using spindle motor power and eddy current for the detection of tool conditions in milling processes [PDF]

, 2015
This paper investigates the use of the power of the driving motor of a CNC spindle in comparison to two perpendicular eddy current sensors for the detection of tool wear in milling processes. Monitoring the power through the current profile is a low cost
Abbass, JK, Al-Habaibeh, A
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Wood Crosscutting Process Analysis for Circular Saws

BioResources, 2016
This article deals with the influence of some cutting parameters (geometry of cutting edge, wood species, and circular saw type) and cutting conditions on the wood crosscutting process carried out with circular saws.
Jozef Krilek, Ján Kováč, Marián Kučera   +2 more
doaj   +1 more source

Modelling and simulation of the dynamic cutting process and surface topography generation in nano/micro cutting [PDF]

, 2008
In nano/micro cutting process, the surface quality is heavily dependent on all the dynamic factors in machining including those from the material, tooling, cutting parameters, servo accuracy, mechanical structure deformation, and non-linear factors as ...
Cheng, K, Zhou, L
core  

A polyhedral approach for the Equitable Coloring Problem [PDF]

, 2011
In this work we study the polytope associated with a 0,1-integer programming formulation for the Equitable Coloring Problem. We find several families of valid inequalities and derive sufficient conditions in order to be facet-defining inequalities.
Bahiense, Campêlo, Daniel Severín, Das, Graciela Nasini, Isabel Méndez-Díaz, Januschowski, Kaibel, Kierstead, Kubale, Lih, Margot, Meyer, Méndez-Díaz, Pemmaraju, Tucker   +15 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cutting Forces and Chip Morphology in Medium Density Fiberboard Orthogonal Cutting

BioResources, 2014
The influence of rake angle, cutting speed, and uncut chip thickness on cutting forces and chip morphology in medium density fiberboards orthogonal cutting was investigated.
Yu Teng, Jianwen Ding, Baojin Wang, Xiaolei Guo, Pingxiang Cao   +4 more
doaj   +1 more source

Cutting load capacity of end mills with complex geometry [PDF]

, 2001
Cutting load capacity of cemented carbide end mills with high length-to-diameter ratios is determined from critical geometric and loading parameters, including a stress concentration factor (SCF) to account for serrated edges, which is determined by ...
Asamoah-Attiah, S., Budak, Erhan, Nemes, J. A.   +2 more
core   +1 more source