Results 31 to 40 of about 798,333 (309)

Laboratory Experimental Study on Rock Breaking Efficiency and Stability of PDC Bit

open access: yesShiyou jixie, 2020
In order to evaluate the rock breaking efficiency and stability of the newly developed PDC bit in the target lithologic formation, and guide the optimization, improvement and efficient use of the newly developed PDC bit, full scale laboratory rock ...
Zhang Jiawei   +6 more
doaj  

Simulation and experimental study on micro-cutting silicon carbide crystal with single grain diamond

open access: yesJin'gangshi yu moliao moju gongcheng
ObjectivesThe hardness of silicon carbide is second only to those of diamond, cubic boron nitride, and boron carbide, making its processing very difficult.
Yufei YANG   +5 more
doaj   +1 more source

The cutting behavior of cortical bone in different bone osten cutting angles and depths of cut [PDF]

open access: yes, 2021
Abstract Cortical bones are semi-brittle and anisotropic, this brings the challenge to suppress vibration and avoid undesired fracture in precise cutting processes in surgeries. In this paper, we proposed a novel analytical model to represent cutting processes of cortical bones, and we used to evaluate cutting forces and fracture toughness, and
Yuanqiang Luo   +5 more
openaire   +1 more source

Cutting depth-oriented ductile machining of infrared micro-lens arrays by elliptical vibration cutting

open access: yesOptics Express, 2023
Infrared micro-lens arrays (MLAs) are widely used in advanced optical systems due to their advantages such as low focusing depth and high sensitivity. Elliptical vibration cutting (EVC) is a promising approach for the fabrication of MLAs on infrared brittle materials.
Zhengding Zheng   +7 more
openaire   +2 more sources

Microwave interferometer controls cutting depth of plastics [PDF]

open access: yes, 1969
Microwave interferometer system controls the cutting of plastic materials to a prescribed depth. The interferometer is mounted on a carriage with a spindle and cutting tool.
Heisman, R. M., Iceland, W. F.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Depth of proofs, depth of cut-formulas and complexity of cut formulas

open access: yesTheoretical Computer Science, 1994
The standard cut-elimination procedure for classical predicate logic is modified to make alternation of quantifiers (rather than the number of quantifiers) the main complexity parameter.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Experimental investigation on micromilling of oxygen-free, high-conductivity copper using tungsten carbide, chemistry vapour deposition and single-crystal diamond micro tools [PDF]

open access: yes, 2010
Insufficient experimental data from various micro tools limit industrial application of the micromilling process. This paper presents an experimental comparative investigation into micromilling of oxygen-free, high-conductivity copper using tungsten ...
Cheng, K, Huo, D
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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