Results 41 to 50 of about 798,333 (309)
Influence of Cutting Angle on Temperature Distribution of Cutter
Shiyou jixie, 2021 The failure of cutter is closely related to cutting temperature, and the formation of cuttings has an impact on the performance and life of cutter. This article builds a rock-breaking mechanics model to conduct numerical simulation analysis on rock ...
Zhang Zaixing +4 more
doaj
Cutting Force and Cutting Quality during Tapered Milling of Glass Magnesium Board
Applied Sciences, 2019 In this paper, the effects of tool geometry and cutting parameters on cutting force and quality were investigated during the tapered milling of glass magnesium (MGO) board with diamond cutters. The results were as follows: firstly, both the cutting force
Pingxiang Cao +5 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
On the depth of cutting planes
, 2019 We introduce a natural notion of depth that applies to individual cutting planes as well as entire families. This depth has nice properties that make it easy to work with theoretically, and we argue that it is a good proxy for the practical strength of cutting planes.
Poirrier, Laurent, Yu, James
openaire +2 more sources
Analytical prediction of stability limit in turning operations [PDF]
, 2006 Unstable cutting due to chatter vibrations is one of the most important problems during metal cutting operations. Chatter can be a limitation for productivity and surface quality in turning operations, especially when long and slender tools and parts are
Budak, Erhan, Ozlu, Emre, Özlü, Emre
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Development of temperature statistical model when machining of aerospace alloy materials [PDF]
, 2012 This paper presents to develop first-order models for predicting the cutting temperature for end-milling operation of Hastelloy C-22HS by using four different coated carbide cutting tools and two different cutting environments.
Bakar Rosli Abu +4 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
High-Power Laser Cutting of Steel Plates: Heat Affected Zone Analysis
Advances in Materials Science and Engineering, 2016 The thermal effect of CO2 high-power laser cutting on cut surface of steel plates is investigated. The effect of the input laser cutting parameters on the melted zone depth (MZ), the heat affected zone depth (HAZ), and the microhardness beneath the cut ...
Imed Miraoui +2 more
doaj +1 more source
Optimization of multiple performance characteristics in turning using Taguchi’s quality loss function: An experimental investigation [PDF]
, 2013 Cutting force and chip reduction coefficient is the important index of machinability as it determines the power consumption and amount of energy invested in machining actions.
Ashok Kumar Sahoo +3 more
core +1 more source