Results 81 to 90 of about 121,508 (306)
Influence of cutting technology on properties of Ni-Mn-Ga single crystalline actuator elements
, 2022 S.667-670For the production of Ni-Mn-Ga single crystalline actuator elements different cutting technologies (wire eroding, diamond wire cutting, water jet cutting, dicing and sawing) were tested and compared.
Laufenberg, M. +5 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2022 The subject of this thesis is to desing a cutting equipment for cutting wires from wire mesh. In theoretical part the cutting proces and elements which appear in the proces are described. In the practical part these finding are used to create a design of
Valenta, Jan
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Underground Space, 2018 This study presents numerical and experimental models for the analysis of the excavation of soft soils by means of a cutting tool. The computational model is constructed using an Updated Lagrangean (UL) velocity-based Finite Element approach.
Abdiel Ramon Leon Bal +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Automation of assessment of the strain state of metal cutting machine mechanism elements on the basis of response function application [PDF]
MATEC Web of Conferences, 2019 The article dwells upon the assessment of the strain state of metal-cutting machines with the help of the numerical method of finite elements in the form of displacements.
Kosov Mikhail +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Identification Algorithm for Instantaneous Engaged Cutting Edge Elements in Five-Axis Milling
, 2011 An identification algorithm for instantaneous engaged cutting edge elements in five-axis milling is presented in this paper. An application of curve and surface intersection is used for filtering the engaged cutting edge elements roughly on any cutter ...
Jian Yong Li +3 more
core +1 more source