Results 51 to 60 of about 53,986 (258)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
In this study, cutter vibrations, wear conditions and cutting forces are observed during jet-assisted turning under coolant pressure conditions. Inconel 718 material is used as a thread.
Orhan GÜNGÖR, Hüseyin Bilal MACİT
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
This article presents the results of an experimental study of cutting forces during face finishing of high-strength spheroidal graphite cast iron EN-GJS-600-3 using a Sandvik Coromant R200-051Q22-12H face milling cutter with round carbide inserts ...
S.I. Radkevych, V.M. Ruban
doaj +1 more source
When machining difficult-to-cut metal materials often used to make sheet metal forming tools, excessive cutting force jumps often break the cutting edge. Therefore, this research developed a system of three neural network models to accurately predict the
Uroš Župerl, Miha Kovačič
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Determination of Optimum Machining Parameters in Machining Rene 41 Superalloy Depending on Cutting Speed [PDF]
Rene 41 superalloy developed to withstand severe mechanical stresses and high temperature operation, and are widely used in aircraft and space vehicles, especially nickel-based ones, due to their high corrosion resistance.
Altin Abdullah +3 more
doaj +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Force modeling in metal cutting is important for various purposes, including thermal analysis, tool life estimation, chatter prediction, and tool condition monitoring.
Bashistakumar M., Pushkal B.
doaj +1 more source

