Results 91 to 100 of about 54,101 (258)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Online Tool Wear Monitoring by the Analysis of Cutting Forces in Transient State for Dry Machining of Ti6Al4V Alloy

open access: yesMetals, 2019
In this work, the analysis of the cutting speed and feed rate influence on tool wear and cutting forces in Ti6Al4V alloy dry machining is presented. The study has been focused on the machining in a transient state.
Yezika Sánchez Hernández   +3 more
doaj   +1 more source

Some Effects of the Cutting Fluid on Cutting Force

open access: yesJournal of the Japan Society of Precision Engineering, 1966
各種の組成を有する切削油剤を用いて, 切削油剤の潤滑効果と冷却効果が, 切削抵抗に及ぼす影響を調べた。超硬バイトによる車軸鋼の切削の場合につき, 普通鋼の高温における機械的性質の変化を考慮に入れて考察した。またそれらに関連して, 切削油剤の作用について, 定性的に一般的考察をした。1) 削り速度20m/min~40m/minにおいては, いずれの切削油剤も有効であるが, 中でも, 極圧潤滑性に富むものの方が, 冷却性に富むものより有効である。水だけでも明らかに切削抵抗を軽減する作用はあるが, その変動係数は比較的大きく, 特に, 削り速度20m/minの場合には, 乾切削の場合よりも大きい。2) 削り速度40m/min以上においては, 塩素系添加剤のものは効果を失い, かえって切削抵抗は高くなる ...
Ryozo FURUICHI, Kentaro TAMAMURA
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Impact of cutting forces on surface quality in finish face milling of compacted graphite iron with CBN and nitride ceramic tools

open access: yesТехнічна інженерія
The article presents the results of studies to determine the influence of cutting forces on the quality parameters of machined surfaces as a result of finishing face milling of products made of compacted graphite cast iron (CGI) using round cutting ...
S.I. Radkevych
doaj   +1 more source

Influence of Cutting Interactions on Cutting Force of a Pick

open access: yesAASRI Procedia, 2012
Abstract Various mechanical excavators have been used for rock cutting. The cutting drum of an excavation machine normally consists of a large number of cutting picks. Accurate calculation of cutting force on individual picks is important to machine design and control. In rock cutting, cuts between picks can interact with each other.
Sun, Yong, Li, X.S.
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Impact Of Cutting Tool Materials On Cutting Force

open access: yes, 2011
{"references": ["D.I. Lalwani, N.K. Mehta, P.K. Jain, \"Experimental investigations of\ncutting parameters influence on cutting forces and surface roughness in\nfinish hard turning of MDN250 steel\", journal of materials processing\ntechnology, vol. 206, pp. 167-179, 2008.", "Y.K. Chou, M.M. Barash, C.J.
Kamely, M. A., Noordin, M. Y.
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

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