Results 91 to 100 of about 1,450,296 (288)

The Investigation of The Effect of Cryogenic Processed PVD and CVD Coated Cutting Tools on Machinability in Turning on Hastelloy X Super Alloy

Gazi Üniversitesi Fen Bilimleri Dergisi, 2017
Super alloys are alloys which has the resistance of high temperatures. In addition to that, super alloys are widely used in aerospace, aviation industries, also in gas turbines because of their high creep strength and high corrosion resistance.
Gültekin UZUN, Selçuk YAGMUR, İhsan KORKUT, Ulvi ŞEKER   +3 more
doaj  

Simultaneous Clamping and Cutting Force Measurements with Built-In Sensors

Sensors, 2020
The intensity of the clamping force during milling operations is very important, because an excessive clamping force can distort the workpiece, while inadequate clamping causes slippage of the workpiece.
Sina Rezvani, Chang-Ju Kim, Simon S. Park, Jihyun Lee   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Machinability analysis on helical milling of carbon fiber reinforced polymer

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2015
In the helical milling process, a rotating tool traverses a helical trajectory to generate a hole. In order to investigate the cutting state in helical milling of carbon fiber reinforced polymer(CFRP), experiments were conducted with unidirectional and ...
Haiyan WANG, Xuda QIN, Hao LI
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A new approach of high speed cutting modelling: SPH method [PDF]

, 2006
The purpose of this study is to introduce a new approach of high speed cutting numerical modelling. A lagrangian Smoothed Particle Hydrodynamics (SPH) based model is carried out using the Ls-Dyna software.
J. Limido, Salaün, Michel, J.L. Lacome, Lacome, Jean-Luc, M. Salaun, C. Espinosa, Espinosa, Christine, Limido, Jérôme   +7 more
core   +1 more source

Measurement of Wood Cutting Forces during Bandsawing Using Piezoelectric Dynamometer

Drvna Industrija, 2016
Optimization of wood cutting conditions can decrease the cutting forces, which directly relates to the energy consumption. The aim of this study was to measure cutting force components in bandsaw processing of green oak and beech wood at 90°-90° cutting ...
Payam Moradpour, Frieder Scholz, Kazem Doosthoseini, Asghar Tarmian   +3 more
doaj   +1 more source

Predictive Cutting Force Model and Cutting Force Chart for Milling with Cutter Axis Inclination

International Journal of Automation Technology, 2013
A force model for milling with cutter axis inclination is presented. The model predicts the cutting force and chip flow direction. Three-dimensional chip flow is interpreted as a piling up of the orthogonal cuttings in the planes containing the cutting velocities and the chip flow velocities in the inclined coordinate system with a ball end mill.
Takashi Matsumura, Motohiro Shimada, Kazunari Teramoto, Eiji Usui   +3 more
openaire   +1 more source