Results 111 to 120 of about 1,450,593 (288)

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Online Tool Wear Monitoring by the Analysis of Cutting Forces in Transient State for Dry Machining of Ti6Al4V Alloy

Metals, 2019
In this work, the analysis of the cutting speed and feed rate influence on tool wear and cutting forces in Ti6Al4V alloy dry machining is presented. The study has been focused on the machining in a transient state.
Yezika Sánchez Hernández, F. Javier Trujillo Vilches, Carolina Bermudo Gamboa, Lorenzo Sevilla Hurtado   +3 more
doaj   +1 more source

Influence of Cutting Interactions on Cutting Force of a Pick

AASRI Procedia, 2012
Abstract Various mechanical excavators have been used for rock cutting. The cutting drum of an excavation machine normally consists of a large number of cutting picks. Accurate calculation of cutting force on individual picks is important to machine design and control. In rock cutting, cuts between picks can interact with each other.
Sun, Yong, Li, X.S.
openaire   +1 more source

Experimental investigation of hydrodynamics of melt layer during laser cutting of steel [PDF]

, 2011
In laser cutting process, understanding of hydrodynamics of melt layer is significant, because it is an important factor which controls the final quality. In this work, we observed hydrodynamics of melt layer on kerf front in the case of laser cutting of
Remy Fabbro, Koji Hirano, FABBRO, Rémy, HIRANO, Koji   +3 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Impact of cutting forces on surface quality in finish face milling of compacted graphite iron with CBN and nitride ceramic tools

Технічна інженерія
The article presents the results of studies to determine the influence of cutting forces on the quality parameters of machined surfaces as a result of finishing face milling of products made of compacted graphite cast iron (CGI) using round cutting ...
S.I. Radkevych
doaj   +1 more source

Cutting Forces in basic and real life wood machining processes review, COST Action E35 2004-2008: Wood machining - Micromechanics and fracture [PDF]

, 2009
The data available in the literature concerning wood cutting forces permit to build models or to simulate the main wood machining processes (milling, sawing, peeling etc.). This approach contributes to a better understanding of formation of wood surfaces
MARCHAL, Rémy, MOTHE, Frédéric, DENAUD, Louis, BLERON, Laurent, Denaud, Louis-Etienne, THIBAUT, Bernard   +5 more
core  

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source