Results 51 to 60 of about 53,986 (258)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Investigation of the Relationship between Vibration, Cutting Forces and Tool Wear During the Processing of Inconel 718 Super Alloy under Coolant Pressure Jet-Assisted Turning with Variance Analysis

open access: yesMehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, 2020
In this study, cutter vibrations, wear conditions and cutting forces are observed during jet-assisted turning under coolant pressure conditions. Inconel 718 material is used as a thread.
Orhan GÜNGÖR, Hüseyin Bilal MACİT
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The effect of cutting conditions, insert coating type, and cooling on cutting forces during face finish milling of high-strength spheroidal grade cast iron

open access: yesТехнічна інженерія
This article presents the results of an experimental study of cutting forces during face finishing of high-strength spheroidal graphite cast iron EN-GJS-600-3 using a Sandvik Coromant R200-051Q22-12H face milling cutter with round carbide inserts ...
S.I. Radkevych, V.M. Ruban
doaj   +1 more source

Artificial Neural Network System for Predicting Cutting Forces in Helical-End Milling of Laser-Deposited Metal Materials

open access: yesTehnički Glasnik, 2023
When machining difficult-to-cut metal materials often used to make sheet metal forming tools, excessive cutting force jumps often break the cutting edge. Therefore, this research developed a system of three neural network models to accurately predict the
Uroš Župerl, Miha Kovačič
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Determination of Optimum Machining Parameters in Machining Rene 41 Superalloy Depending on Cutting Speed [PDF]

open access: yesE3S Web of Conferences
Rene 41 superalloy developed to withstand severe mechanical stresses and high temperature operation, and are widely used in aircraft and space vehicles, especially nickel-based ones, due to their high corrosion resistance.
Altin Abdullah   +3 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Finite Element Analysis of Orthogonal Cutting Forces in Machining AISI 1020 Steel Using a Carbide Tip Tool

open access: yesЖурнал інженерних наук, 2018
Force modeling in metal cutting is important for various purposes, including thermal analysis, tool life estimation, chatter prediction, and tool condition monitoring.
Bashistakumar M., Pushkal B.
doaj   +1 more source

Home - About - Disclaimer - Privacy