Results 51 to 60 of about 1,505,269 (297)
Estimates of the bistable region in metal cutting [PDF]
, 2008 The classical model of regenerative vibration is investigated with new kinds of nonlinear cutting force characteristics. The standard nonlinear characteristics are subjected to a critical review from the nonlinear dynamics viewpoint based on the ...
Dombovari, Zoltan +4 more
core +1 more source
Applied Sciences, 2023 This paper aims to provide essential guidance for the crashworthiness design of cutting energy-absorbing structures for subway vehicles. By investigating tool failure with experiment and numerical approaches, a new energy-absorbing tube structure was ...
Qianchen Gao +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Identification of tool failure modes in drilling Udimet® 720 superalloy [PDF]
, 2011 The ACCENT Project (FP7- AAT- 2007- RTD-1) will allow the European Aero Engine manufacturers to improve their competitiveness by applying adaptive control techniques to the manufacturing of their components.
Dutilh, Vincent +3 more
core
Toward a better understanding of tool wear effect through a comparison between experiments and SPH numerical modelling of machining hard materials [PDF]
, 2009 The aim of this study is to improve the general understanding of tungsten carbide (WC–Co) tool wear under dry machining of the hard-to-cut titanium alloy Ti6Al4V. The chosen approach includes experimental and numerical tests.
Salaün, Michel +17 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Modelling and simulation of the dynamic cutting process and surface topography generation in nano/micro cutting [PDF]
, 2008 In nano/micro cutting process, the surface quality is heavily dependent on all the dynamic factors in machining including those from the material, tooling, cutting parameters, servo accuracy, mechanical structure deformation, and non-linear factors as ...
Cheng, K, Zhou, L
core +4 more sources
Effect of Needle Milling Modes on Machining Productivity
Наука и техника, 2003 The paper presents results of experimental research pertaining to effect of needle milling modes on productivity.It has been ascertained that rates of cutting Vt tension i and micro cutting tool sweep L make an effect on machining productivity.It is ...
I. L. Barshaj
doaj +1 more source