Results 51 to 60 of about 42,092 (305)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied Sciences, 2023 This paper aims to provide essential guidance for the crashworthiness design of cutting energy-absorbing structures for subway vehicles. By investigating tool failure with experiment and numerical approaches, a new energy-absorbing tube structure was ...
Qianchen Gao +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Adhesion resistance of nanocoatings of tool working surfaces [PDF]
MATEC Web of Conferences, 2020 To increase the strength, reliability, durability of the cutting tool, various wear-resistant coatings are applied to its cutting part. At the same time, under cutting conditions, it is necessary to ensure a high degree of adhesion of the coating to this
Frolenkova Larissa +4 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Identification of tool failure modes in drilling Udimet® 720 superalloy [PDF]
, 2011 The ACCENT Project (FP7- AAT- 2007- RTD-1) will allow the European Aero Engine manufacturers to improve their competitiveness by applying adaptive control techniques to the manufacturing of their components.
Dutilh, Vincent +3 more
core
, 2020 International audienceBroussonetiapapyrifera leaf protein was used as a biomass feedstock to prepare wood adhesives, and the influence of cutting modes (cutting frequencies and cutting heights) on leaf protein content and reactivity was studied in this ...
Xia, Yufang +6 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Improving the finishing face milling process of flat surfaces of small width parts
Технічна інженерія, 2021 Face mills equipped with superhard materials find more and more wide application at finishing of high hardness materials. These tools fully reveal the potential at high-speed processing.
H.M. , O.A. , N.O. , L.Ye.
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source