Results 111 to 120 of about 2,078,237 (349)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Anisotropy of Single-Crystal Silicon in Nanometric Cutting

Nanoscale Research Letters, 2017
The anisotropy exhibited by single-crystal silicon in nanometric cutting is very significant. In order to profoundly understand the effect of crystal anisotropy on cutting behaviors, a large-scale molecular dynamics model was conducted to simulate the ...
Zhiguo Wang, Jiaxuan Chen, Guilian Wang, Qingshun Bai, Yingchun Liang   +4 more
doaj   +1 more source

Point Cloud Classification by Domain Adaptation Using Recycling Max Pooling and Cutting Plane Identification. [PDF]

Sensors (Basel), 2023
Yoo H, Jun K.
europepmc   +1 more source

Utilisation of Single Tooth Procedures to Establish the Cutting Mechanics of Woodworking Hand-saw Teeth [PDF]

The work reported in this thesis details the original research undertaken by the author into the cutting mechanics of wood-working handsaw tooth geometries. The research can be separated into three distinctive sections.
Naylor, Andrew
core  

A cutting plane algorithm for minimum perfect 2-matchings [PDF]

, 1987
A cutting plane algorithm for minimum perfect 2-matchings / by M. Grötschel, O. Holland. - In: Computing. 39. 1987. S.
Grötschel, Martin, Holland, Olaf
core   +1 more source

Experimental Investigation on the Effects of Cutting Direction and Joint Spacing on the Cuttability Behaviour of a Conical Pick in Jointed Rock Mass

Applied Sciences
In this study, a series of rock cutting tests was conducted using a conical pick to investigate the effect of joints on roadheader performance. Tests were performed on intact rock and jointed rock mass specimens with three different joint spacings.
Han-Eol Kim, Min-Seong Kim, Wan-Kyu Yoo, Chang-Yong Kim   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Significance of cutting plane in liquid metal embrittlement severity quantification. [PDF]

SN Appl Sci, 2021
DiGiovanni C, He L, Hawkins C, Zhou NY, Biro E.   +4 more
europepmc   +1 more source

IMPLEMENTATION OF AN INTERIOR POINT CUTTING PLANE ALGORITHM [PDF]

, 2008
In this thesis, first we propose a new approach to solve Semi Infinite Linear Optimization Problems (SILP). The new algorithm uses the idea of adding violated cut or cuts at each iteration.
Ghaffari, Hamid
core