Results 111 to 120 of about 1,171,807 (293)
Solving the Max-Cut Problem using Semidefinite Optimization in a Cutting Plane Algorithm.
, 2008 A central graph theory problem that occurs in experimental physics, circuit layout, and computational linear algebra is the max-cut problem. The max-cut problem is to find a bipartition of the vertex set of a graph with the objective to maximize the ...
Sullivan, Eric Joseph
core
Numerical simulation on fragmentation of heterogeneous granite by axe-shaped PDC cutter
Jin'gangshi yu moliao moju gongchengObjectivesPolycrystalline diamond compact (PDC) bits are extensively utilized in the drilling industry. However, conventional PDC cutters are prone to failure when drilling through granite formations, leading to reduced drilling efficiency.
Jiajun LU +4 more
doaj +3 more sources
MathematicsIn this study, we proposed proximal analytic center cutting plane algorithms for solving variational inequalities whose domains are normal regions. Our algorithms stop with a solution of the variational inequality after a finite number of iterations, or ...
Renying Zeng
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Research and Realization of Medical Volume Data Interactive Cutting
Journal of Algorithms & Computational Technology, 2010 Medical image visualization is an important field of scientific computing visualization. Three-dimensional segmentation plays a very important role in three-dimensional reconstruction of human tissues and region of interest.
Wu Jian +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Lubrication in metal cutting under built-up edge conditions [PDF]
The effect of a mineral oil lubricant and sulphur (an EP additive) on machining of medium carbon steel has been investigated. The lubricant was applied with several different concentrations an additive containing sulphur. The concentrations were 0%, 1 %
Bacci Da Silva, Marcio
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2012 This paper presents a 2D convergence density criterion for minimizing the total junction delay at isolated junctions in the lane-based optimization framework.
C. K. Wong, Y. Y. Lee
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source