Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Effect of visual disruption on the lower limb kinematic and kinetic characteristics in athletes after anterior cruciate ligament reconstruction. [PDF]
Yu P +5 more
europepmc +1 more source
On Typically-Real Functions in a Cut Plane [PDF]
openaire +2 more sources
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
A Segmentation-Assisted Three-Dimensional Planning Workflow for Static-Guided Pterygoid Implant Placement: A Proof-of-Concept Report. [PDF]
David AP +5 more
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Methods for designing patient-specific templates for optimized fitting of autologous bone augmentations in alveolar cleft osteoplasty. [PDF]
Schröder TA +9 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
CAD-Based Analysis and Experimental Validation of Registration Errors in Imageless Total Knee Arthroplasty. [PDF]
Sohail M, Khalid S, Elahi MU, Kim HS.
europepmc +1 more source
Processing second-order stochastic dominance models using cutting-plane representations
Csaba I. Fábián, G. Mitra, Diana Roman
semanticscholar +1 more source

