Results 61 to 70 of about 191,202 (337)

Stabbing Planes [PDF]

open access: yes, 2018
We introduce and develop a new semi-algebraic proof system, called Stabbing Planes that is in the style of DPLL-based modern SAT solvers. As with DPLL, there is only one rule: the current polytope can be subdivided by branching on an inequality and its ...
Beame, Paul   +6 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Number of Plane Corner Cuts

open access: yesAdvances in Applied Mathematics, 1999
An \(n\)-element subset \(\lambda\) of \(\mathbb{N}^2\) which is cut off a line is called a (plane) corner cut of size \(n\). Let be \({\mathbb{N}^2\choose n}_{ \text{cut}}\) the set of corner cuts of size \(n\). [See \textit{S. Onn} and \textit{B. Sturmfels}, ibid., 29-48 (1999; above).] The authors give a generating for the number \(\#{\mathbb{N}^2 ...
Corteel, Sylvie   +3 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Orbital Conflict: Cutting Planes for Symmetric Integer Programs [PDF]

open access: diamond, 2021
Jeff Linderoth   +4 more
openalex   +1 more source

Cutting Planes for Signomial Programming

open access: yesSIAM Journal on Optimization
Cutting planes are of crucial importance when solving nonconvex nonlinear programs to global optimality, for example using the spatial branch-and-bound algorithms. In this paper, we discuss the generation of cutting planes for signomial programming. Many global optimization algorithms lift signomial programs into an extended formulation such that these
Liding Xu   +3 more
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

SIMULATION STUDY AND STRENGTH VALIDATION OF PLANES’LOAD AT DIFFERENT POSITIONS OF COAL PLOUGH

open access: yesJixie qiangdu, 2017
Planes are the execution tools of coal plough,the work load directly affecting the planing capacity and production efficiency of the plow. In order to study the load characteristics,developing the coal plow load calculation program based on Matlab and VC,
ZHAO LiJuan, CHEN Lei, TIAN Zhen
doaj  

Relaxations of mixed integer sets from lattice-free polyhedra [PDF]

open access: yes, 2018
This paper gives an introduction to a recently established link between the geometry of numbers and mixed integer optimization. The main focus is to provide a review of families of lattice-free polyhedra and their use in a disjunctive programming ...
Del Pia, Alberto, Weismantel, Robert
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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