Results 81 to 90 of about 23,957 (296)

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

Optimizing Cutting Planes for Advanced Joining and Additive Manufacturing [PDF]

open access: yes, 2017
While additive manufacturing allows more complex shapes than conventional manufacturing processes, there is a clear benefit in leveraging both new and old processes in the definition of metal parts. For example, one could create complex part shapes where
Brandon Massoni, Matthew I. Campbell
core   +1 more source

Analysis of the Technological Parameters of the Heat Exchanger in the Heating Pipe

open access: yesMATEC Web of Conferences, 2017
The main purpose of this article is to analyze the selecting of technological parameters for the heat exchanger to improve the heat transfer and reduce the noise during operation in the heating pipe, which is used in the different systems of the planes ...
Knyazev Vladimir, Bubnov Gregory
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A Cutting Method with Updating Approximating Sets and its Combination with Other Algorithms

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2014
For solving constrained minimization problem propose a cutting plane method which belongs to a class of cutting methods.The designed method uses an approximation of the epigraph of the objective function.
I.Ya. Zabotin, R.S. Yarullin
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Studying mechanism of anisotropic crack generation on C-, R-, A-, and M-planes of sapphire during ultra-precision orthogonal cutting using a visualized slip/fracture activation model

open access: yesNanotechnology and Precision Engineering
With the growing demand for the fabrication of microminiaturized components, a comprehensive understanding of material removal behavior during ultra-precision cutting has become increasingly significant.
Suk Bum Kwon, Sangkee Min
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Geometrical analysis of thread milling – Part 1: Evaluation of tool angles [PDF]

open access: yes, 2010
Thread milling is a method which is increasingly used for machining thread. For this operation, a helical interpolation is required. Furthermore, the thread mill is a tool whose geometry is rather complex.
FROMENTIN, Guillaume, POULACHON, Gerard
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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