Results 81 to 90 of about 2,777,990 (323)

SIMULATION STUDY AND STRENGTH VALIDATION OF PLANES’LOAD AT DIFFERENT POSITIONS OF COAL PLOUGH

Jixie qiangdu, 2017
Planes are the execution tools of coal plough,the work load directly affecting the planing capacity and production efficiency of the plow. In order to study the load characteristics,developing the coal plow load calculation program based on Matlab and VC,
ZHAO LiJuan, CHEN Lei, TIAN Zhen
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Analytic Center Cutting Plane Method with Semidefinite Cuts

SIAM Journal on Optimization, 2003
Summary: We analyze an analytic center cutting plane algorithm for convex feasibility problems with semidefinite cuts. The problem of interest seeks a feasible point in a bounded convex set, which contains a full-dimensional ball with radius \(\varepsilon
Mohammad R. Oskoorouchi, Jean-Louis Goffin   +1 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A cutter path generation strategy for helical surface machining of screw rotor

Science Progress, 2020
In this article, the disk mill cutter path generation strategy for the machining of complex helical surface via a currently developed minimal orientation-distance algorithm based on spatial discretization method is studied. The strategy proposed here is,
Yuchun Kuang, Wei Lin, Zongzheng Dong, Longmei Wu, Qin Wang   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On Using Cutting Planes in Pseudo-Boolean Optimization

, 2006
Cutting planes are a well-known, widely used, and very eective technique for Integer Linear Programming (ILP). However, cutting plane techniques are seldom used in Pseudo-Boolean Optimization (PBO) algorithms.
Marques-Silva, J. P., Manquinho, V., Vasco M. Manquinho, João Marques-Silva   +3 more
core  

Analysis of the Technological Parameters of the Heat Exchanger in the Heating Pipe

MATEC Web of Conferences, 2017
The main purpose of this article is to analyze the selecting of technological parameters for the heat exchanger to improve the heat transfer and reduce the noise during operation in the heating pipe, which is used in the different systems of the planes ...
Knyazev Vladimir, Bubnov Gregory
doaj   +1 more source