Results 191 to 200 of about 39,747 (262)

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

"Dealer's Choice": Univalve Location Effect on Skin Surface Pressures in Long Leg Casts. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Quinn R, Baker C, Ditmars H, Ignacio G, Schlechter JA.   +4 more
europepmc   +1 more source

FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model

Advanced Science, EarlyView.
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble, Wiktor Zywicki, Enrico Lucarelli, Ania Naila Guerrieri, Francesca Taraballi, Gianluca Cidonio, Claudia Di Bella, Carmine Onofrillo, Andrea J. O'Connor, Serena Duchi   +9 more
wiley   +1 more source

Nitrogen and Boron Co-Doped Graphene Oxide Quantum Dots: Top-Down Fabrication, Comprehensive Characterization and Antibacterial Activity Against Multidrug-Resistant ESKAPE Pathogens. [PDF]

ACS Omega
Mikhraliieva A, Bragina O, Xing Y, Karpichev Y, Zaitsev V.   +4 more
europepmc   +1 more source

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

Advanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee, Jumi Kim, Taehan Yoon, So Hyun Kwon, Su Chan Park, Dohyun Chun, Dohyeong Kim, Eun Jung Park, Hyunwoo Kim, Ji Min Lee   +9 more
wiley   +1 more source

A Multimodal Approach to Addictive-Like Behavior in Stock Trading: A Case Report. [PDF]

Cureus
Saradha S, Kumar R, Sharma MK.
europepmc   +1 more source

Expanded Hepatic Progenitor Cells Featured with Aggregation of α‐Synuclein Contribute to Pathologic Bile Duct Regeneration in Biliary Atresia

Advanced Science, EarlyView.
Expanded NCAM1+EpCAM+ hepatic progenitor cells in biliary atresia are characterized by aggregation of α‐synuclein. This pathological protein potentiates cellular susceptibility to GSH‐dependent redox dyshomeostasis, induces unstable biliary cell fate specification, and subsequently drives aberrant biliary regeneration.
Hua Xie, Mengyan Zhu, Zhongxian Zhu, Jiaqi Tang, Ruyi Zhang, Zequan Ding, Junzhi Li, Zhongluan Wu, Paul Kwong Hang Tam, Qianghu Wang, Vincent Chi Hang Lui, Yankai Xia, Weibing Tang   +12 more
wiley   +1 more source

Anatomical relationship between the intertrochanteric line and femoral neck osteotomy level in direct anterior approach total hip arthroplasty: a 3D morphometric and cadaveric validation study. [PDF]

Arthroplasty
Limmahakhun S, Runraksar S, Kitcharanant N, Jingjit W.   +3 more
europepmc   +1 more source

Assessing Mitochondrial Respiratory Complex-Associated Function From Previously Frozen Mouse Placental Tissue. [PDF]

Bio Protoc
Podinic T, Xhuti D, Monaco C, Nederveen JP, Raha S.   +4 more
europepmc   +1 more source