Research on cutting mechanism and process optimization method of gear skiving
Scientific ReportsThe cutting force and cutting temperature have a significant impact on the service life and durability of gear skiving cutters. Due to unreasonable design, the existing process parameters lead to dramatically nonuniform cutting force and cutting ...
Peng Wang +5 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Closure to “Discussions of ‘Temperature Distribution at Tool-Chip and Tool-Work Interface in Metal Cutting’” (1958, Trans. ASME, 80, pp. 318–319) [PDF]
, 1958 B. T. Chao, K. J. Trigger
openalex +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Using the Finite Element Method to Determine the Temperature Distributions in Hot-wire Cutting. [PDF]
, 2011 Hot-wire cutting is a common material removal process used to shape and sculpt plastic foam materials, such as expanded polystyrene (EPS). Due to the low cost and sculpt-ability of plastic foams they are popular materials for large sized (> 1 m³ ...
Aitchison, David +1 more
core
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Prediction of Temperature Distribution in Orthogonal Machining Based on the Mechanics of the Cutting Process Using a Constitutive Model [PDF]
, 2018 Jinqiang Ning, Steven Y. Liang
openalex +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Температура резания при сверлении пакетов углепластик/титановый сплав [PDF]
, 2015 В статье выполнен анализ существующих методов измерения температуры различных конструкционных материалов, в том числе и композиционных. Показано, что определение температуры на вращающемся сверле при резании неэлектропроводных материалов является задачей,
Колесник, В. А. +2 more
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source