Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
An expert mill cutter and cutting parameters selection system incorporating a control strategy
This paper discusses the selection of tools and cutting parameters in milling operations. To carry out this research, an expert system has been developed based on numerical methods of performance evaluation.
De la Sen, Manuel +5 more
core +1 more source
Experimental study on the effect of CNT-enriched nanofluid lubrication on the performance of textured cutting tool in the turning of aluminum 7075 alloy. [PDF]
Khani S.
europepmc +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
A predictive model for the cutting force in wood machining developed using mechanical properties
In this study a number of work piece variations were evaluated whilst limiting the cutting conditions. Eight wood species controlled at four moisture levels were machined along and across the wood grain.
Andrew Naylor, +7 more
core
Design and Modeling of a Miniature Hydraulic Motor for Powering a Cutting Tool for Minimally Invasive Procedures. [PDF]
Vinnakota M +3 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Remaining Useful-Life Prediction of the Milling Cutting Tool Using Time-Frequency-Based Features and Deep Learning Models. [PDF]
Sayyad S +4 more
europepmc +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Transfer Learning-Based Condition Monitoring of Single Point Cutting Tool. [PDF]
Naveen Venkatesh S +6 more
europepmc +1 more source

