Results 101 to 110 of about 940,967 (310)
Tool separates sleeve-type unions without heat [PDF]
, 1966 Tool that uses conventional milling and cutting techniques separates sleeve type tubing unions and tubes without using heat.
Millett, A. U.
core +1 more source
Photographs of Cutting-Tools in Action [PDF]
Proceedings of the Institution of Mechanical Engineers, 1905 n ...
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Geometrical analysis of thread milling – Part 1: Evaluation of tool angles [PDF]
, 2010 Thread milling is a method which is increasingly used for machining thread. For this operation, a helical interpolation is required. Furthermore, the thread mill is a tool whose geometry is rather complex.
FROMENTIN, Guillaume, POULACHON, Gérard
core +2 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Dynamic analysis of runout correction in milling [PDF]
, 2010 Tool runout and its effects is an important area of research within modelling, simulation, and control of milling forces. Tool runout causes tool cutting edges to experience uneven forces during milling.
Diez Cifuentes, Eduardo +3 more
core +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Multiobjective Optimization of Tool Geometric Parameters Using Genetic Algorithm
Complexity, 2018 Tool geometric parameters have a huge impact on tool wear. Up to now, there are only a few researches on tool geometric parameters and optimization, and the single objective function of parameter optimization used by researchers during high-speed ...
Maohua Du +3 more
doaj +1 more source
Expert System Based on Integrated Fuzzy AHP for Automatic Cutting Tool Selection
Applied Sciences, 2019 Cutting tool selection plays an important role in achieving reliable quality and high productivity work, and for controlling the total cost of manufacturing.
Xuan Lan Phung +2 more
doaj +1 more source
Experimental characterization of friction coefficients at the tool-chip-workpiece interface in cutting: Evaluation of lubrication efficiency of mineral oil [PDF]
, 2010 Collaboration avec le LTDS/ENISEThe characterization of friction coefficients at the tool-chip-workpiece interface remains an issue. This paper presents a new experimental set-up able to simulate similar tribological phenomena as the ones occurring at ...
CLAUDIN, Christophe +4 more
core +2 more sources