Results 81 to 90 of about 940,967 (310)
Journal of the Institution of Production Engineers, 1939 info:eu-repo/semantics ...
openaire +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
DESIGNING AND DEVELOPING A PROGRAM IN SINUMERIK vs. 1.3 FOR A SHAFT WITH SEALING GROOVES [PDF]
Fiabilitate şi Durabilitate, 2015 CNC is an abbreviation for „Computer Numerically Controlled". Numerically controlled tool machines are also called CNC machines.The numeric control results in a process of continuous „feeding” of an especially built programable controller, with a set ...
VALERIA VICTORIA IOVANOV
doaj
Threaded pilot insures cutting tool alignment [PDF]
, 1966 Threaded pilot allows machining of a port component, or boss, after the reciprocating hole has been threaded.
Goldman, R., Schneider, W. E.
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Machinability improvement using high-pressure cooling in turning
Research in Agricultural Engineering, 2014 Process fluids are used primarily for their cooling and lubricating effect in machining. Many ways to improve their performance have been proposed; the analysis of some of them is provided in the paper.
R. Drlička, V. Kročko, M. Matúš
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Identifying the cause of cutting tool failure by using simulation software
MATEC Web of Conferences, 2018 The article is focused on the construction problems of cutting tools designed for manufacturing components in high numbers. Analysis of the tool with low lifetime is provided with the use of simulation software to detect the causes of the tool failure ...
Zrak Andrej, Koňár Radoslav
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Tool post modification allows easy turret lathe cutting-tool alignment [PDF]
, 1966 Modified tool holder and tool post permit alignment of turret lathe cutting tools on the center of the spindle. The tool is aligned with the spindle by the holder which is kept in position by a hydraulic lock in feature of the tool post. The tool post is
Fouts, L.
core +1 more source