Results 81 to 90 of about 176,368 (313)
Toward a better understanding of tool wear effect through a comparison between experiments and SPH numerical modelling of machining hard materials [PDF]
, 2009 The aim of this study is to improve the general understanding of tungsten carbide (WC–Co) tool wear under dry machining of the hard-to-cut titanium alloy Ti6Al4V. The chosen approach includes experimental and numerical tests.
Salaün, Michel +17 more
core +1 more source
DESIGNING AND DEVELOPING A PROGRAM IN SINUMERIK vs. 1.3 FOR A SHAFT WITH SEALING GROOVES [PDF]
Fiabilitate şi Durabilitate, 2015 CNC is an abbreviation for „Computer Numerically Controlled". Numerically controlled tool machines are also called CNC machines.The numeric control results in a process of continuous „feeding” of an especially built programable controller, with a set ...
VALERIA VICTORIA IOVANOV
doaj
Journal of the Institution of Production Engineers, 1939 info:eu-repo/semantics ...
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
An investigation on micro cutting mechanics: Modelling, simulations and experimental case studies [PDF]
, 2014 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University London.Micro cutting is becoming increasingly important since miniature and micro components/products have become more and more demanded in precision ...
Sawangsri, Worapong
core
Study on Machining Process of Multi-step Holes by Using The Standard Cutting Tool and Stepped Drill
Journal of Applied Engineering and Technological ScienceBesides technological solutions, machining productivity is a factor that it is always considered by manufacturers. The cutting tool (CT) is one of the key points to boost the cutting efficiency and improve machining productivity of the machining process.
V. L. Trinh +3 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Identifying the cause of cutting tool failure by using simulation software
MATEC Web of Conferences, 2018 The article is focused on the construction problems of cutting tools designed for manufacturing components in high numbers. Analysis of the tool with low lifetime is provided with the use of simulation software to detect the causes of the tool failure ...
Zrak Andrej, Koňár Radoslav
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
An investigation on the mechanics of nanometric cutting and the development of its test-bed
, 2003 The mechanics of machining at a very small depth of cut (100 nm or less) is not well understood. The chip formation physics, cutting forces generation, resulting temperatures and the size effects significantly affect the efficiency of the process and ...
Cheng, K, Guo, XJ, Luo, X, Holt, R
core +1 more source