Results 71 to 80 of about 900,172 (360)

Data validation: a case study for a feed-drive monitoring [PDF]

open access: yes, 1999
The monitoring of machine-tools implicated in the metal cutting process is the subject of increasing developments because of requests on control, reliability, availability of machine-tools and on work-piece quality.
Desforges, Xavier   +2 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

New hardenable CERMETS for cutting and forming applications [PDF]

open access: yes, 2008
The University Carlos III has developed a new metal matrix composite (MMC) constituted by a dispersion of ceramic particles of TiCN in a steel matrix. The matrix can be hardened by heat treatment, leading to a material with high hardness and toughness ...
Gordo Odériz, Elena
core   +1 more source

Performance of nano-structured multilayer PVD coating TiAlN/VN in dry high speed milling of aerospace aluminium 7010-T7651 [PDF]

open access: yes, 2005
A low-friction and wear resistant TiAlN/VN multilayer coating with TiAlN/VN bilayer thickness 3 nm has been grown by using the combined cathodic arc etching and unbalanced magnetron sputtering deposition on high speed steel tools for dry cutting of ...
Coldwell   +23 more
core   +1 more source

Cutting tools

open access: yesJournal of the Institution of Production Engineers, 1939
info:eu-repo/semantics ...
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Optimization for preparing Bi1.68Pb0.32Sr1.75Ca1.85Cu2.85O10+y powders by wet ball milling

open access: yesMaterials Research Express, 2022
Superconducting Bi _1.68 Pb _0.32 Sr _1.75 Ca _1.85 Cu _2.85 O _10+ _y (Bi-2223) powders were prepared by a conventional solid-state reaction using hand grinding and wet ball milling.
Yingwei Chen   +8 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Investigating the performance of TiN and TiAIN coatings on milling cutter used for machining bimetal steel strip [PDF]

open access: yes, 2009
Surface engineering of cutting tools (single point or multipoint) through advanced coatings (e.g., TiN) has contributed towards considerable improvement of tool life, productivity and machining quality [1] by modifying the tool substrate.
Haider, Julfikar, Sarwar, Mohammed
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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