Results 91 to 100 of about 52,575 (309)

Experiment and Numerical Simulation on Shale Cutting and Breaking of Special-shaped Cutter

open access: yesShiyou jixie
In order to solve the problems of low rock-breaking efficiency and short service life of PDC bit in drilling shale gas wells, a study was made on the shale cutting and breaking mechanism of special-shaped cutter.Based on typical special-shaped cutters ...
Wen Bo   +4 more
doaj  

Press cuttings of Shell product advertising [70 of many]

open access: yes, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Shell Company of Australia
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Press cuttings of Shell product advertising [23 of many]

open access: yes, 1962
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Shell Company of Australia
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Asexual Propagation of Campanula pelviformis and Petromarula pinnata—Two Local Endemic Plants of Crete with Multipurpose Crop Potential

open access: yesHorticulturae
The urgency for sustainable propagation methods is increasing as anthropogenic disturbances threaten global biodiversity and plant productivity. This study focused on the cutting propagation of Campanula pelviformis and Petromarula pinnata, two local ...
Ioannis Anestis   +7 more
doaj   +1 more source

Press cuttings of Shell product advertising [71 of many]

open access: yes, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Shell Company of Australia
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Press cuttings of Shell product advertising [14 of many]

open access: yes, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Shell Company of Australia
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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