Results 171 to 180 of about 260,054 (360)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Commodity risk assessment of <i>Petunia</i> spp. and <i>Calibrachoa</i> spp. unrooted cuttings from Uganda. [PDF]

EFSA J
EFSA Panel on Plant Health (PLH), Civera AV, Baptista P, Berlin A, Chatzivassiliou E, Cubero J, Cunniffe N, de la Peña E, Desneux N, Di Serio F, Filipiak A, Gonthier P, Hasiów-Jaroszewska B, Jactel H, Landa BB, Maistrello L, Makowski D, Milonas P, Papadopoulos NT, Susi H, van der Gaag DJ, Lacomme C, Debode J, Navas-Cortes JA, Akrivou A, Kritikos C, Kormpi M, Papachristos D, Reppa C, Antonatos S, Beris D, Schulz OM, Lombardo MF, Gardi C, Potting R.   +34 more
europepmc   +1 more source

Evaluation of Physicochemical and Biodegradability Properties of Selected Nigerian Non-Edible Oilseeds as Potential Cutting Fluids

, 2015
Titilope John Jayeoye, Mary B. Ogundiran, D. A. Fadare, A. A. Ogunjobi   +3 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Numerical simulation study of gas-solid two-phase flow characteristics in borehole sampling of coal cuttings. [PDF]

PLoS One
Xue S, Zhang L, Zheng X, Gao C, Liu S.
europepmc   +1 more source

Cutting corners [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2015
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Mini-cutting protocol and anatomical basis of adventitious rooting in Ocotea odorifera. [PDF]

Sci Rep
Da Luz SC, De Alcantara GB, Ribas LLF, Das Almas D, Koehler HS, Zuffellato-Ribas KC.   +5 more
europepmc   +1 more source

Cutting Performance of Lubricants in MQL Machining&mdash;Action Mechanism Based on Tribology&mdash;

, 2010
Toshiaki WAKABAYASHI
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source