Results 91 to 100 of about 8,959 (184)

Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue [PDF]

, 2014
Five-year survival for patients with oral cancer has been disappointingly stable during the last decades, creating a demand for new biomarkers and treatment targets.
A Jemal, A Muller, A Pellegrino, A Zhu, A Zipin-Roitman, AF Ziober, AM Mulligan, BJ Moeller, BK Lo, C Beskow, C Grandi, CC Tong, CJ Hutchings, CL Addison, CT Allen, D Sano, E Montagna, Göran Laurell, HA Wolff, IK Kalnins, J Romanini, J Vandercappellen, J Wang, JN Sarkaria, K Annertz, K Kawada, K Kawada, KA Dinshaw, Karin Nylander, KB Pytynia, L Boldrup, L Goldberg-Bittman, L Lundqvist, Lotta Loljung, M Cojoc, M Fujita, M Liu, M Rentoft, M Rentoft, Matilda Rentoft, MF Calmon, MN Wente, N Sahu, P Silva, Philip John Coates, S Atula, S Friesland, S Matsumura, S Shintani, S Struyf, SP Schantz, SP Schantz, TC Walser, Torben Wilms, W Garavello, WA Yeudall, XL Lu, Y Matsuo   +57 more
core   +4 more sources

Machine Learning Prediction of 90‐Day Mortality in HBV‐Related ACLF Using Olink‐Derived Inflammatory Protein Signatures

Liver International, Volume 45, Issue 12, December 2025.
ABSTRACT Background Hepatitis B virus‐induced acute‐on‐chronic liver failure (HBV‐ACLF) has extremely high mortality rates and is closely linked to inflammatory responses. Early interventions in high‐risk patients can significantly improve survival rates.
Yi Zhang, Lina Sun, Huimin Liu, Ke Shi, Yu Lu, Ying Feng, Xianbo Wang   +6 more
wiley   +1 more source

Salivary Fractalkine Differentiating Periodontitis from Periodontally Healthy Subjects

International Journal of Dentistry
Objective. The chemokine “Fractalkine” (CX3CL1) and its corresponding receptor (CX3CR1), chemokine belonging to the CX3C family, have an essential role in developing several systemic inflammatory disorders.
Omer Mohammed Harbood, Raghad Fadhil Abbas   +1 more
doaj   +1 more source

Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation

Frontiers in Aging Neuroscience, 2017
Alzheimer’s disease (AD) is characterized by a progressive cognitive decline and believed to be driven by the self-aggregation of amyloid-β (Aβ) peptide into oligomers and fibrils that accumulate as senile plaques.
Cláudia Caldeira, Carolina Cunha, Ana R. Vaz, Ana R. Vaz, Ana S. Falcão, Andreia Barateiro, Elsa Seixas, Adelaide Fernandes, Adelaide Fernandes, Dora Brites, Dora Brites   +10 more
doaj   +1 more source

Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1.

The Journal of biological chemistry, 1998
Fractalkine is a multimodular human leukocyte chemoattractant protein and a member of the chemokine superfamily. Unlike other human chemokines, the chemokine domain of fractalkine has three amino acids between two conserved cysteines, referred to as the CX3C motif. Both plasma membrane-associated and shed forms of fractalkine have been identified. Here,
C, Combadiere, K, Salzwedel, E D, Smith, H L, Tiffany, E A, Berger, P M, Murphy   +5 more
openaire   +1 more source

Chemokine expression and viral infection of the central nervous system: regulation of host defense and neuropathology. [PDF]

, 2001
An effective host response against viral infection of the central nervous system (CNS) is the principal factor dictating the outcome of infection. It is the responsibility of the immune response to contain and control viral replication. Paradoxically, it
Lane, TE, Liu, MT
core  

Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators [PDF]

, 2009
Objective: Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1α (Ccl3/MIP-1α) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
Berberich, Nina, Bihari, Peter, Khandoga, Alexander G., Krombach, Fritz, Lerchenberger, Max, Rehberg, Markus, Reichel, Christoph A., Zahler, Stefan   +7 more
core   +1 more source

Human and bovine respiratory syncytial virus vaccine research and development [PDF]

, 2008
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine, Meyer, Gilles, Schelcher, François   +2 more
core   +2 more sources

Inflammatory Responses are Sex Specific in Chronic Hypoxic–Ischemic Encephalopathy

Cell Transplantation, 2018
Neonatal hypoxic–ischemic encephalopathy (HIE) is increasingly recognized as a sexually dimorphic disease. Male infants are not only more vulnerable to ischemic insult; they also suffer more long-term cognitive deficits compared with females with ...
Abdullah Al Mamun, Haifu Yu, Sharmeen Romana, Fudong Liu   +3 more
doaj   +1 more source

Structure-based discovery of novel US28 small molecule ligands with different modes of action [PDF]

, 2017
The human cytomegalovirus-encoded G protein-coupled receptor US28 is a constitutively active receptor, which can recognize various chemokines. Despite the recent determination of its 2.9 Å crystal structure, potent and US28-specific tool compounds are ...
Abrahamian, Amarandi, Ballesteros, Bento, Billstrom, Burg, Casarosa, Chee, Ferreira, Fox, Graham, Hauge, Hesselgesser, Hulshof, Irwin, Jensen, Katritch, Kledal, Kralj, Kralj, Kralj, Maussang, O'Boyle, Qin, Rasmussen, Rosenkilde, Rosenkilde, Rosenkilde, Schwartz, Spiess, Streblow, Tan, Thiele, Thiele, Thiele, Totrov, Tschammer, Vischer, Vomaske, Waldhoer, Wise, Wu   +41 more
core   +2 more sources