Results 101 to 110 of about 8,959 (184)

Inhibition of ginsenoside Re on pulmonary fibrosis induced by bleomycin in mice: Involved in modulating the CX3CL1/CX3CR1 axis

European Journal of Medicinal Chemistry Reports
Pulmonary fibrosis (PF) is a common pathological feature of a variety of diffuse, progressive and irreversible pulmonary interstitial diseases, and effective therapeutic agents are currently lacking.
Zhaoqin Wen, Huiyun Yang, Hong Ling, Huicai Lin, Xiaoyan Chen, Wan-Lan Shi, Yongxiang Song, Jiang Deng   +7 more
doaj   +1 more source

Fractalkine/CX3CR1 axis is critical for neuroprotection induced by hypoxic postconditioning against cerebral ischemic injury

Cell Communication and Signaling
Microglial activation-mediated neuroinflammation is a major contributor to neuronal damage after cerebral ischemia. The Fractalkine (FKN)/CX3C chemokine receptor 1 (CX3CR1) axis plays a critical role in regulating microglial activation and ...
Lixuan Zhan, Meiqian Qiu, Jianhua Zheng, Meijing Lai, Kunqin Lin, Jiahua Dai, Weiwen Sun, En Xu   +7 more
doaj   +1 more source

Cytokines and therapy in COPD: a promising combination? [PDF]

, 2002
COPD is a major health problem, with patients showing a progressively declining, largely irreversible, change in lung function. This is associated with chronic airways inflammation and structural remodeling, including loss of alveolar ...
Boer, W.I. (Pim) de
core   +1 more source

Chemokine CX3C motif receptor 1 (CX3CR1) [PDF]

Science-Business eXchange, 2010
openaire   +3 more sources

Peritoneal Dialysis Aggravates and Accelerates Atherosclerosis in Uremic ApoE−/− Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atherosclerosis is highly prevalent in people with chronic kidney disease (CKD), including those receiving peritoneal dialysis (PD). Although it is lifesaving, PD induces profound systemic inflammation, which may aggravate atherosclerosis ...
Jamie Kane, Winnie G. Vos, Laura A. Bosmans, Bram W. van Os, Myrthe den Toom, Sanne Hoeksema‐Hackmann, Denise Moen‐de Wit, Marion J. Gijbels, Linda Beckers, Aldo Grefhorst, Johannes H. M. Levels, Lily Jakulj, Marc G. Vervloet, Esther Lutgens, Etto C. Eringa   +14 more
doaj   +1 more source

Killing two birds with one drug: a new application for HIV-1 cell entry inhibitors in the treatment of metastatic cancer. [PDF]

, 2005
The chemokine receptors CCR5 and CXCR4 serve as co-receptors for the human immunodeficiency virus 1 (HIV-1) and thus, are important cellular components during HIV-1 cell entry. In recent years, a new biological role for chemokine receptors has emerged in
Bachmann, Andre S, Gamper, Ivonne
core  

Multi-omics Analysis Reveals Molecular Subtype of Mitochondrial Oxidative Stress and Prognostic Model Development in Sepsis

Frontiers in Bioscience-Landmark
Background: Sepsis is a prevalent disease with high mortality involving severe systemic inflammatory responses. Although the mechanisms underlying sepsis have been widely explored, the occurrence and exacerbation of sepsis remain ...
Baolong Zhu, Jinxiang Wang, Yan Wang
doaj   +1 more source

IL-8 Induces a Transient Arrest of Rolling Eosinophils on Human Endothelial Cells [PDF]

, 2000
Eosinophils exhibit a rolling interaction with E-selectin-expressing endothelium, and need to be activated by inflammatory me-diators to firmly adhere to this surface.
Joosten, Dianne P.H., Koenderman, L., Lammers, J.W.J., Linden, J.A.M. van der, Ulfman, L.H., Zwaginga, Jaap Jan   +5 more
core   +1 more source

Growth and apoptosis pathways in human cutaneous melanoma: in vitro and in vivo studies by using biological and proteomics approaches [PDF]

, 2013
Purpose. Melanoma is the most aggressive cutaneous cancer without effective treatment. Diagnosis is achieved very often too late and prognosis is poor.
ROSSI, STEFANIA
core  

CX3C Chemokine Receptor 1 [PDF]

, 2020
openaire   +1 more source