Results 171 to 180 of about 41,078 (248)

A Transcriptomic Analysis of Cancer‐Stromal Interactome in Lung Cancer Xenograft Models

open access: yesCancer Science, Volume 117, Issue 3, Page 841-851, March 2026.
We conducted a comprehensive analysis of the lung cancer interactome to identify key ligand–receptor pairs involved in the aggressiveness of lung adenocarcinoma. Tumor necrosis factor superfamily member 12 and its receptor tumor necrosis factor receptor superfamily member 12A signaling axis may be potential candidates for therapeutic intervention for ...
Yuriko Takayama‐Isagawa   +16 more
wiley   +1 more source

Tui Na Acupressure Modulates Treg Immunosuppression via FoxP3/mTORC1 Signalling in ALS Mice

open access: yesImmunology, Volume 177, Issue 3, Page 481-500, March 2026.
The proposed mechanism by which Tui Na acupressure improves motor and cognitive dysfunction in ALS mice by activating the FoxP3/mTORC1 pathway. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease driven by neuroinflammation, where regulatory T cell (Treg) dysfunction exacerbates immune imbalance.
Jie Han   +7 more
wiley   +1 more source

Old Blood, Young Bones: Identification of Middle‐Aged Myeloid Cells That Limit Cortical Bone Loss

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Although studies support disrupted bone remodelling within geriatric populations, mid‐life changes are understudied. To investigate this, we performed bone marrow transplantation assays using either 8‐ or 40‐week‐old mice. Micro‐CT analyses of lethally irradiated 8‐week‐old mice transplanted with 40‐week‐old bone marrow exhibited increased mid‐
Jinsha Koroth   +6 more
wiley   +1 more source

A High‐Resolution Transcriptomic Atlas of Cell Types in the Ventral Visual Thalamus

open access: yesJournal of Neurochemistry, Volume 170, Issue 3, March 2026.
Visual information from the eyes travels from retinal ganglion cells (RGCs) to reach the brain through several relay centers. One of these centers, the ventral lateral geniculate nucleus (vLGN), is much less understood than others. In this study, we created the first detailed map of the different cell types found in the mouse vLGN.
Katelyn Stebbins   +5 more
wiley   +1 more source

Erratum to "<i>CX3CR1</i> <sup>+</sup> Monocytes/Macrophages Promote Regional Immune Injury in Mesangial Proliferative Glomerulonephritis through Crosstalk with Activated Mesangial Cells". [PDF]

open access: yesResearch (Wash D C)
Zhang J   +20 more
europepmc   +1 more source

Adrenarche as a regulator of sensitivity to early adversity

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract The human brain is highly sensitive to early adversity, which can have long‐term consequences for later mental health. It is also a time of rapid learning of social, motor and other skills, including language. It is proposed that pre‐adrenarche, the only epoch in human development in which cortisol is not accompanied by dehydroepiandrosterone (
J. Herbert
wiley   +1 more source

High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion. [PDF]

open access: yesNat Commun
de Menezes MN   +13 more
europepmc   +1 more source

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