Results 211 to 220 of about 18,860 (236)
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Clinical Toxicology, 1981
In recent years, the increasing use of laetrile has been added to the traditional sources of exposure to cyanide in industry, chemistry labs, and fumigation. The events in Jonestown in 1978 were a grim reminder of the lethality of cyanide. Nonetheless, advancement in new modes of treatment has been slow.
S N, Vogel, T R, Sultan, R P, Ten Eyck
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In recent years, the increasing use of laetrile has been added to the traditional sources of exposure to cyanide in industry, chemistry labs, and fumigation. The events in Jonestown in 1978 were a grim reminder of the lethality of cyanide. Nonetheless, advancement in new modes of treatment has been slow.
S N, Vogel, T R, Sultan, R P, Ten Eyck
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Pediatric Critical Care Medicine, 2006
Cyanide intoxication is an extremely rare event. We report a case of a teenager presenting with unresponsiveness, hemodynamic instability, and profound anion gap metabolic acidosis secondary to elevated lactate levels. It was later confirmed that he was a victim of cyanide poisoning.Individual case report.Pediatric intensive care unit of a tertiary ...
Donald H. Shaffner +2 more
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Cyanide intoxication is an extremely rare event. We report a case of a teenager presenting with unresponsiveness, hemodynamic instability, and profound anion gap metabolic acidosis secondary to elevated lactate levels. It was later confirmed that he was a victim of cyanide poisoning.Individual case report.Pediatric intensive care unit of a tertiary ...
Donald H. Shaffner +2 more
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Treatment of Cyanide Poisoning
Military Medicine, 1991The object of this study was to evaluate the effectiveness of five regimens in treating cyanide poisoning. A series of anesthetized adult beagle dogs were instrumented to record hemodynamic and respiratory function and given 2.5 mg/kg sodium cyanide intravenously. The 10 control animals given only cyanide died at from 5 to 7 minutes.
Harry Froehlich, James A. Vick
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Hydroxocobalamin in cyanide poisoning
Clinical Toxicology, 2012On theoretical grounds, hydroxocobalamin is an attractive antidote for cyanide poisoning as cobalt compounds have the ability to bind and detoxify cyanide. This paper reviews the pharmacokinetic and pharmacodynamic aspects of hydroxocobalamin, its efficacy in human cyanide poisoning and its adverse effects.PubMed was searched for the period 1952 to ...
Timothy Clive Marrs, John P Thompson
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Cyanide Poisoning— A Challenge
Archives of Internal Medicine, 1977It is now over 40 years since Chen and his associates 1 published a classic report on the treatment of cyanide poisoning using dogs as the animal model. Until the current report of Graham et al in this issue (see p 1051), this therapeutic regimen was virtually unchallenged as the definitive treatment for cyanide poisoning in humans. The presentation by
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The Lancet, 2009
In May, 2005, a 32-year-old woman lost consciousness soon after drinking a non-alcoholic beverage. She was transported to hospital within 5 min, found to be unresponsive, and intubated. Before intubation, blood gas measurements on room air (possible venous sample), were: pH 7·846, pCO2 24·2 mm Hg, pO2 28·7 mm Hg, HCO3 41·8 mmol/L (base excess [BE] 26 ...
Yi-Jung Yu +3 more
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In May, 2005, a 32-year-old woman lost consciousness soon after drinking a non-alcoholic beverage. She was transported to hospital within 5 min, found to be unresponsive, and intubated. Before intubation, blood gas measurements on room air (possible venous sample), were: pH 7·846, pCO2 24·2 mm Hg, pO2 28·7 mm Hg, HCO3 41·8 mmol/L (base excess [BE] 26 ...
Yi-Jung Yu +3 more
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Cyanide Poisoning Deaths in Dogs
Journal of Veterinary Medicine Series A, 2006SummaryIn 2005, the deaths of three dogs were reported in Erdek, Turkey. Examining appropriate historical and clinical signs, postmortem findings and the discovery of cyanide in their stomachs and intestinal contents and livers supported a diagnosis of cyanide poisoning.
Ozyigit, MUSA ÖZGÜR +3 more
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Therapeutic Problems in Cyanide Poisoning
Journal of Toxicology: Clinical Toxicology, 1987In three patients with severe acute cyanide poisoning, a cyanosis was observed instead of the bright pink skin coloration often mentioned as a sign in textbooks. Treatment of cardiopulmonary insufficiency is as essential as antidotal therapy and the use of sodium nitrite and 4-DMAP is not without risk as, in practice, the methemoglobin-level induced is
van Heijst, ANP +4 more
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Cyanide poisoning and antidotes
Emergency Medicine Australasia, 2012Abstract : We read with interest the review article by Reade et. al titled, Review article: Management of cyanide poisoning. The article was a succinct review of current treatment guidelines for cyanide treatment. We concur with several of the authors' recommendations that had not been clearly stated in other reviews or reports. In particular, we agree
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Antidotes for Acute Cyanide Poisoning
Current Pharmaceutical Biotechnology, 2012Cyanide poisoning can present in multiple ways, given its widespread industrial use, presence in combustion products, multiple physical forms, and chemical structures. The primary target of toxicity is mitochondrial cytochrome oxidase. The onset and severity of poisoning depend on the route, dose, physicochemical structure and other variables.
Stephen W. Borron, Frédéric J. Baud
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