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Antagonism of cyanide poisoning by dihydroxyacetone
Toxicology Letters, 2002Dihydroxyacetone (DHA) effectively antagonized the lethal effect of cyanide in mice and rabbits, particularly if administered in combination with thiosulfate. Oral DHA (2 and 4 g/kg) given to mice 10 min before injection (i.p.) of cyanide increased the LD50 values of cyanide from 5.7 mg/kg to 12 and 17.6 mg/kg, respectively.
Esmaeel Ghelichkhani, Hossein Niknahad
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Cyanide poisoning as a mode of suicide
Forensic Science, 1978Abstract A five-year survey (1970–1975) of suicides was conducted in a county of 1,800,000 population. Cyanide is readily available in various forms, lethal in minute quantities and rapidly acting. Out of 700 suicides, six employed cyanide poisoning as an active manner of death.
Charles L. Winek +3 more
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The Treatment of Cyanide Poisoning in Children
Pediatrics, 1970The widely published schedule for the treatment of cyanide poisoning by the nitrite thiosulfate method of Chen is based on adult work and is potentially lethal for children under 25 kg in weight. Unless a dose of sodium nitrite appropriate for the amount of hemoglobin in the child is chosen, lethal methemoglobinemia may result.
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Cyanide Poisoning and Methaemoglobinaemia
Acta Pharmacologica et Toxicologica, 1947openaire +3 more sources