Results 111 to 120 of about 5,502,726 (361)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Mathematics, 2018 It is the case that, in certain applications of fuzzy graphs, a t-norm, instead of a minimum, is more suitable. This requires the development of a new theory of fuzzy graphs involving an arbitrary t-norm in the basic definition of a fuzzy graph. There is
John N. Mordeson, Sunil Mathew
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Classical Business Cycles in America: Are National Business Cycles Synchronised? [PDF]
This paper provides further evidence on the synchronization between business cycle regimes in seven American countries by using a classical business cycles approach. Despite recent increasing international economic transactions within this continent, our
Mejia-Reyes, P.
core
Business, Housing and Credit Cycles
Social Science Research Network, 2018 We use multivariate unobserved components models to estimate trend and cyclical components in GDP, credit volumes and house prices for the U.S. and the five largest European economies.
Gerhard Rünstler, Marente Vlekke
semanticscholar +1 more source
Graphs and Combinatorics, 2020 For any graph $G$, let $ι_{\rm c}(G)$ denote the size of a smallest set $D$ of vertices of $G$ such that the graph obtained from $G$ by deleting the closed neighbourhood of $D$ contains no cycle. We prove that if $G$ is a connected $n$-vertex graph that is not a triangle, then $ι_{\rm c}(G) \leq n/4$. We also show that the bound is sharp. Consequently,
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Innovation and Business Cycles [PDF]
The main purpose of this chapter is to assess the originality of Schumpeter's theory of business cycles. The first section outlines the distinctive features of Schumpeter's approach to business cycles and economic dynamics.
Agnès Festré
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The Regularity of Business Cycles [PDF]
Do business cycles have predictable periodicities or are they random walks without past regularities or predictive value? Arguments in support of either position are found in the literature, with no apparent convergence to an agreement.
Victor Zarnowitz
core