Results 171 to 180 of about 1,540,620 (269)

Ovarian follicle dynamics in the plains zebra (Equus quagga). [PDF]

PLoS One
Barros LO, Hyde KA, Gazzaniga N, Gastal MO, Aguiar FLN, Carneiro GF, Gastal EL.   +6 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effect of Freeze-Thaw Cycle Times on Basic Properties and Bond Performance with Steel Reinforcement of Tunnel Lining Concrete in the Tibetan Plateau. [PDF]

Materials (Basel)
Zang Y, Zhan Y, Guo D, Liang S, Zhao Q, Tao Q, Yu H.   +6 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Pulmonary Fibrosis and Pulmonary Function in Patients with Metastatic Testicular Cancer During and after Combination Chemotherapy: The BLEOTOX Study. [PDF]

Eur Urol Open Sci
Frey L, Grunwald S, Ruckes C, Duwe G, Wohlleber K, Frey LJ, Haack M, Rölz N, Dotzauer R, Korczynski D, Axel Haferkamp A, Brandt MP.   +11 more
europepmc   +1 more source

Asymptotic Cycles

The Annals of Mathematics, 1957
openaire   +2 more sources

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Impact of home-based port infusion versus hospital-based peripheral infusion on anxiety, quality of life, and emergency visits in gastrointestinal cancer: a prospective observational study by the Turkish Oncology Group (TOG). [PDF]

Support Care Cancer
Cetin OA, Karaoglu T, Alkan A, Yavuzsen T, Tanriverdi O.   +4 more
europepmc   +1 more source

Comparative Study on the Engineering Performance of Lime- and Cement-Improved Argillaceous Siltstone. [PDF]

Materials (Basel)
Chen Y, Huang F, Zhan R, Zhou M, Weng H, Yang H.   +5 more
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source