Results 231 to 240 of about 87,778 (377)

Dissecting stress-activated protein kinase (SAPK)-signaling pathways using multiplex gene knockout HeLa cells. [PDF]

J Biol Chem
Ito C, Yamamoto M, Yokota N, Nakamura N, Shiomi M, Kizu M, Ichinose M, Fujii S, Fujii T, Fukunaga R.   +9 more
europepmc   +1 more source

Cyclic‐AMP‐dependent protein kinase A regulates apoptosis by stabilizing the BH3‐only protein Bim

EMBO Reports, 2011
Diane Moujalled, R. Weston, H. Anderton, Robert L. Ninnis, P. Goel, A. Coley, D. Huang, Li Wu, A. Strasser, H. Puthalakath   +9 more
semanticscholar   +1 more source

From Yeast to Therapeutics: Modeling Neurodegenerative Diseases in Saccharomyces cerevisiae

Yeast, EarlyView.
Yeast plasmids expressing human Aβ‐42, α‐syn, htt, and TDP‐43. Their fate includes an equilibrium between the endocytic pathway and aggregates that potentially disrupt endocytosis, vesicular transport, vacuolar autophagy, and mitochondrial activity. ABSTRACT Here, we review the use of Saccharomyces cerevisiae as a powerful model organism for studying ...
Jose Ribamar Ferreira‐Junior, Vittoria de Lima Camandona, Mario H. Barros   +2 more
wiley   +1 more source

Metabolic crossroads in insulin resistance: exploring lipid dysregulation and inflammation. [PDF]

Front Immunol
Saadati S, Godini R, Reddy A, Teede H, Mousa A.   +4 more
europepmc   +1 more source

Role of 3':5'-cyclic-AMP-dependent protein kinase in regulation of protein synthesis in reticulocyte lysates.

Proceedings of the National Academy of Sciences of the United States of America, 1977
A. Datta, C. de Haro, J. M. Sierra, S. Ochoa   +3 more
semanticscholar   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

ATP Metabolism of Astrocytes: Consumption, Regeneration and Restoration. [PDF]

Neurochem Res
Dringen R, Karger G, Winkler U, Hirrlinger J.   +3 more
europepmc   +1 more source

Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.

, 1987
Michel Bouvier, L.M. Fredrik Leeb-Lundberg, Jeffrey Benovic, Marc G. Caron, Robert J. Lefkowitz   +4 more
openalex   +1 more source

A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells.

Proceedings of the National Academy of Sciences of the United States of America, 1975
J. Hochman, P. Insel, H. Bourne, P. Coffino, G. Tomkins   +4 more
semanticscholar   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source