Results 251 to 260 of about 64,381 (295)
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Cyclic AMP-dependent protein kinases of bovine epididymal spermatozoa
Biochemical and Biophysical Research Communications, 1972Abstract Cyclic AMP-dependent protein kinase (cAMP-PrK) activity, some 100-fold greater than that in extracts of other bovine tissues, has been found in sonicates of bovine epididymal spermatozoa. A less than 20-fold purification of the enzyme yields a preparation migrating as three components, two of which possess protein kinase activity, by ...
D D, Hoskins +2 more
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An unusual cyclic AMP-dependent protein kinase from nematodes
Biochemical and Biophysical Research Communications, 1984The search for an unusual cyclic nucleotide-dependent protein kinase in nematodes represented an attempt to gain some insight into the proposed homology of the cAMP and cGMP-dependent protein kinases. Two species of protein kinase were found in high speed supernatants of the mycophagous nematode Aphelenchus avenae.
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Inhibition of cyclic AMP dependent protein kinase by vanadyl sulfate
JBIC Journal of Biological Inorganic Chemistry, 2006Vanadium salts influence the activities of a number of mammalian enzymes in vitro but the mechanisms by which low concentrations of vanadium ameliorate the effects of diabetes in vivo remain poorly understood. The hypothesis that vanadium compounds act by inhibiting protein tyrosine phosphatases has attracted most support.
Kioumars A, Jelveh +2 more
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Effect of cyclic AMP-dependent protein kinases on gene expression
Advances in Enzyme Regulation, 1982Mechanisms for regulating activation of cyclic AMP-dependent protein kinase were investigated and a possible biological role of this enzyme was elucidated. Autophosphorylation of cyclic AMP-dependent protein kinase was shown to occur via an intramolecular mechanism: the regulatory subunit undergoes phosphorylation only within the holoenzyme.
E S, Severin, M V, Nesterova
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Cyclic AMP-Dependent and Cyclic GMP-Dependent Protein Kinases of Nervous Tissue
1981Publisher Summary This chapter focuses on cyclic AMP (cAMP)-dependent and cyclic GMP (cGMP) -dependent protein kinases of nervous tissue. Information about cAMP-dependent and cGMP-dependent protein kinases of brain has increased considerably over the last few years. It is now fairly well established that two types of cAMP-dependent protein kinase and
U, Walter, P, Greengard
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Reversible inhibition of cyclic AMP-dependent protein kinase by insulin
Molecular and Cellular Biochemistry, 1978Extracts of fasted rat diaphragms, previously treated with or without insulin were assayed for glycogen synthase, protein kinase and cyclic [3H]-AMP binding. Treatment with insulin produced an elevation in the % of glycogen synthase I and a concurrent decrease in cyclic AMP-dependent protein kinase activity and cyclic [3H]-AMP binding.
R J, Walkenbach, R, Hazen, J, Larner
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Effect of indomethacin on the cyclic AMP-dependent protein kinase
European Journal of Pharmacology, 1980Indomethacin inhibited cyclic AMP-dependent protein kinase activity in small intestine in in vivo experiments. An inverse pattern of variation was exhibited by acetyl salicylic acid, eterylate and benorylate, acetyl-p-amino-phenol being inactive. Indomethacin, acetyl salicylic acid, eterylate and benorylate increased the protein kinase activity in ...
R E, Catalán +4 more
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Cyclic AMP-dependent and -independent protein kinases in HeLa cells
Archives of Biochemistry and Biophysics, 1980Abstract The protein kinase activities of HeLa cell cytosol have been characterized. Differentiation between cyclic AMP-dependent and -independent kinase activities was achieved by the use of purified specific cyclic AMP-dependent protein kinase inhibitor.
J P, Gray, R A, Johnson, D L, Friedman
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Indomethacin in submicromolar concentrations inhibits cyclic AMP-dependent protein kinase
Nature, 1978INDOMETHACIN is a potent inhibitor of prostaglandin synthesis1,2, and has been used to demonstrate indirectly the mediation of biological events by prostaglandins. The rationale for this use of indomethacin has been supported when analytical techniques for direct prostaglandin quantitation have been used3,4. There are, however, conflicting data. A role
H S, Kantor, M, Hampton
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Inactivation of phosphofructokinase 2 by cyclic AMP-dependent protein kinase
Biochemical and Biophysical Research Communications, 1981Abstract Treatment with the catalytic subunit of cyclic AMP-dependent protein kinase induced the following modifications in the kinetic properties of purified phosphofructokinase 2. The affinity for Fru-6-P, the Vmax and the stimulatory effect of Pi were decreased; the inhibitory actions of P-enol-pyruvate and citrate were increased; the pH activity ...
E, Van Schaftingen +2 more
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