Results 291 to 300 of about 87,778 (377)

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source

The structure and activity of cyclic AMP-dependent protein kinase A

Journal of Animal and Feed Sciences, 2000
openaire   +1 more source

PLAGL1 overexpression exacerbates type 1 diabetes by inducing β‐cell apoptosis via oxidative stress‐dependent dual DNA damage and cGAS/STING pathway activation

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) arises from autoimmune destruction of pancreatic β‐cells. Pleomorphic adenoma gene‐like 1 (PLAGL1) overexpression has been linked to β‐cell apoptosis, but molecular mechanisms remain incompletely understood.
Cheng Li, Lingyan Qiao, Juan Ge, Sicui Hu, Hongxiu Yang, Conghui Hu, Tang Li   +6 more
wiley   +1 more source

Therapeutic potential of adenosine receptor modulators in cancer treatment. [PDF]

RSC Adv
Maity P, Ganguly S, Deb PK.
europepmc   +1 more source

Metabolic regulation of interferon-mediated innate antiviral immunity. [PDF]

Front Immunol
Zhong T, Cao Q, Ma Z, Jiang C.
europepmc   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

N3A motifs in RIβ mediate allosteric crosstalk between cAMP and ATP in PKA activation. [PDF]

Protein Sci
Wu J, Bruystens JGH, Sahoo P, Bubis J, Maillard RA, Taylor SS, Ilouz R.   +6 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

The role of AMPK signaling pathway in the pathogenesis of type 2 diabetes mellitus with its complications and related metabolic disorders. [PDF]

Metabol Open
Hunie Tesfa K, Desalegn Gebeyehu C, Tadele Ewunetie A, Gugsa E, Nigatu Zewdie A, Dessie G, Tezera Endale H.   +6 more
europepmc   +1 more source

Active Endothelial Inactivation of Hyperpermeability: The Role of Nitric Oxide-Driven cAMP/Epac1 Signaling. [PDF]

J Cardiovasc Dev Dis
Lillo MA, Burboa PC, Durán WN.
europepmc   +1 more source