Results 321 to 330 of about 87,778 (377)
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Inhibition of cyclic AMP dependent protein kinase by vanadyl sulfate
JBIC Journal of Biological Inorganic Chemistry, 2006Vanadium salts influence the activities of a number of mammalian enzymes in vitro but the mechanisms by which low concentrations of vanadium ameliorate the effects of diabetes in vivo remain poorly understood. The hypothesis that vanadium compounds act by inhibiting protein tyrosine phosphatases has attracted most support.
Kioumars A, Jelveh +2 more
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Cyclic AMP-dependent protein kinase from Ustilago maydis
Molecular and Cellular Biochemistry, 1984Ustilago maydis was surveyed for cyclic AMP-dependent protein kinase activity. Using a combination of ion-exchange and molecular filtration techniques, we demonstrate that there is only one form of cyclic AMP-dependent protein kinase in the cytosolic fraction of the fungus.
N, Kerner, S, Passeron
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Effect of cyclic AMP-dependent protein kinases on gene expression
Advances in Enzyme Regulation, 1982Mechanisms for regulating activation of cyclic AMP-dependent protein kinase were investigated and a possible biological role of this enzyme was elucidated. Autophosphorylation of cyclic AMP-dependent protein kinase was shown to occur via an intramolecular mechanism: the regulatory subunit undergoes phosphorylation only within the holoenzyme.
E S, Severin, M V, Nesterova
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Reversible inhibition of cyclic AMP-dependent protein kinase by insulin
Molecular and Cellular Biochemistry, 1978Extracts of fasted rat diaphragms, previously treated with or without insulin were assayed for glycogen synthase, protein kinase and cyclic [3H]-AMP binding. Treatment with insulin produced an elevation in the % of glycogen synthase I and a concurrent decrease in cyclic AMP-dependent protein kinase activity and cyclic [3H]-AMP binding.
R J, Walkenbach, R, Hazen, J, Larner
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Distribution of cyclic AMP-dependent protein kinase in the bovine cornea
Experimental Eye Research, 1981Soluble and particulate fractions of bovine corneal epithelium, stroma and endothelium were prepared and assayed for protein kinase activity. All preparations exhibited measurable activity in the absence of cyclic AMP (cyclic AMP-independent activity) as well as significant enzyme stimulation in its presence (cyclic AMP-dependent activity).
R J, Walkenbach, R D, LeGrand, R E, Barr
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Inactivation of phosphofructokinase 2 by cyclic AMP-dependent protein kinase
Biochemical and Biophysical Research Communications, 1981Abstract Treatment with the catalytic subunit of cyclic AMP-dependent protein kinase induced the following modifications in the kinetic properties of purified phosphofructokinase 2. The affinity for Fru-6-P, the Vmax and the stimulatory effect of Pi were decreased; the inhibitory actions of P-enol-pyruvate and citrate were increased; the pH activity ...
E, Van Schaftingen +2 more
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Cyclic AMP-dependent and -independent protein kinases in HeLa cells
Archives of Biochemistry and Biophysics, 1980Abstract The protein kinase activities of HeLa cell cytosol have been characterized. Differentiation between cyclic AMP-dependent and -independent kinase activities was achieved by the use of purified specific cyclic AMP-dependent protein kinase inhibitor.
J P, Gray, R A, Johnson, D L, Friedman
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Cyclic AMP-dependent and independent protein kinases in Ascaridia galli
Molecular and Biochemical Parasitology, 1984The occurrence of multiple protein kinases, distinguished with respect to molecular weight and preference for acceptor proteins, was demonstrated in Ascaridia galli. The molecular weights of the cyclic AMP-dependent protein kinase and of phosvitin kinase I and II - both independent of cyclic AMP-were determined to be 160000, greater than 200000 and ...
E, Ossikovski, R D, Walter
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Cyclic AMP-dependent protein kinase in calf-snout epidermis
Archives of Dermatological Research, 1986The biochemical characteristics of cyclic AMP-dependent protein kinase in calf-snout epidermis were investigated. The activity of cyclic AMP-dependent protein kinase was higher in the lower layer than the upper layer of epidermis. The supernatant of homogenates of the lower layer of calf-snout epidermis was fractionated by DEAE-cellulose chromatography
K, Ikai, J S, McGuire
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Cyclic AMP, cyclic AMP-dependent protein kinase, and the regulation of gene expression
Life Sciences, 1977Abstract Biological responses produced by cAMP in mammalian cells are remarkably diverse and differ profoundly from one cell type and tissue to another. However, it is thought at this time that all effects of cAMP are mediated through the activation of cAMP-dependent protein kinases.
R A, Jungmann, D H, Russell
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