Results 31 to 40 of about 913,001 (226)

Factors associated with hand joint destruction in Chinese patients with rheumatoid arthritis

BMC Musculoskeletal Disorders, 2017
Background There have been no previous report of hand joint destruction prevalence in Chinese rheumatoid arthritis (RA) patients. Therefore, the aim of this study was to investigate the prevalence and potential factors of hand joint destruction among RA ...
Lijuan Zhang, Jing Wang, Qiuxiang Zhang, Ting Fu, Rulan Yin, Ze Wang, Liren Li, Xianhua Wu, Zhifeng Gu   +8 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

The Diagnostic Utility of Anti-cyclic Citrullinated Peptide Antibodies, Matrix Metalloproteinase-3, Rheumatoid Factor, Erythrocyte Sedimentation Rate, and C-reactive Protein in Patients with Erosive and Non-erosive Rheumatoid Arthritis

Clinical and Developmental Immunology, 2005
Objective: To compare the diagnostic utility of laboratory variables, including matrix metalloproteinase-3 (MMP-3), anti-cyclic citrullinated peptide (CCP) antibodies, rheumatoid factor (RF), erythrocyte sedimentation rate (ESR),
O. Shovman, B. Gilburd, G. Zandman-Goddard, Y. Sherer, H. Orbach, R. Gerli, Y. Shoenfeld   +6 more
doaj   +1 more source

Cyclic Citrullinated Peptide Aptamer Treatment Attenuates Collagen-Induced Arthritis

, 2022
We describe the study of a novel aptamer-based candidate for treatment of seropositive rheumatoid arthritis. The candidate is a nanoparticle-formulated cyclic citrullinated peptide aptamer, which targets autoantibodies and/or the immune reactions leading
Astakhova, K., Rethi, Bence, Pedersen, N., Chronakis, Ioannis S., Rethi, B., Khatri, S., Chronakis, I, Kragstrup, Tue, Hansen, J, Pedersen, N, Kragstrup, TW, Mendes, A., Catrina, Anca I., Chronakis, I., Keiding, Ulrik Bering, Gram-Nielsen, S, Clausen, MH, Khatri, Sangita, Rethi, B, Gram-Nielsen, S., Hansen, J., Hansen, Jonas, Brandt-Clausen, Idamarie Palsbom, Pedersen, Nadia Bom, Kragstrup, T. W., Keiding, U, Mendes, Ana C., Gram-Nielsen, Sanne, Mendes, A, Clausen, M. H., Khatri, S, Clausen, Mads Hartvig, Astakhova, Kira, Keiding, U.   +33 more
core   +1 more source

Abatacept reduces disease activity of rheumatoid arthritis independently of modulating anti-citrullinated peptide antibody production

Immunological Medicine, 2020
Abatacept may exert its clinical effect on rheumatoid arthritis (RA) by suppressing anti-cyclic citrullinated peptide (CCP) antibody production. This study was undertaken to test this hypothesis by examining the changes of disease activity of RA and anti-
Hisakata Yamada, Tomomi Tsuru, Takeshi Otsuka, Masayuki Maekawa, Hiroshi Harada, Takaaki Fukuda, Hiroshi Tsukamoto, Akira Maeyama, Shigeru Yoshizawa, Ken Wada, Yasuharu Nakashima, Eisuke Shono, Seiji Yoshizawa, Hiroshi Jojima, Masakazu Kondo   +14 more
doaj   +1 more source

Differences in synovial tissue infiltrates between anti–cyclic citrullinated peptide–positive rheumatoid arthritis and anti–cyclic citrullinated peptide–negative rheumatoid arthritis [PDF]

Arthritis & Rheumatism, 2007
AbstractObjectiveTo compare synovial tissue infiltrates from patients with anti–cyclic citrullinated peptide (anti‐CCP)–positive rheumatoid arthritis (RA) with those from patients with anti‐CCP–negative RA.MethodsSynovial tissue samples were obtained arthroscopically from the inflamed knee joints of 57 patients with RA (34 of whom were anti‐CCP ...
van Oosterhout M, Bajema I, Levarht EW, Toes RE, Huizinga TW, van Laar JM   +5 more
openaire   +3 more sources

Immunosensing the rheumatoid arthritis biomarker through bifunctional aldehyde-amine linkers on an iron oxide nanoparticle seeded voltammetry sensor

Nanomaterials and Nanotechnology, 2022
An immunosensor was developed on an interdigitated electrode (IDE) by voltammetry sensing for the early identification of the autoimmune disease ‘rheumatoid arthritis (RA)’ by detecting the biomarker anti-cyclic citrullinated peptide antibody (anti-CCP).
Bowei Zhou, Yonglong Yan, JingBo Xie, Hongbo Huang, Heyun Wang, Subash CB Gopinath, Periasamy Anbu, Sanshan He, Lijun Zhang   +8 more
doaj   +1 more source

Characterization of Autoantigens Targeted by Anti-Citrullinated Protein Antibodies In Vivo: Prominent Role for Epitopes Derived from Histone 4 Proteins. [PDF]

PLoS ONE, 2016
Anti-citrullinated protein antibodies (ACPA) have become an integral part of the clinical definition of rheumatoid arthritis, and are hypothesized to be important in the immunopathogenesis of this autoimmune disease.
Xiaobo Meng, Peyman Ezzati, Irene Smolik, Charles N Bernstein, Carol Ann Hitchon, Hani S El-Gabalawy   +5 more
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Anti-cyclic citrullinated peptide antibodies are not associated with familial Mediterranean fever

, 2010
Objective: This study investigated the presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in familial Mediterranean fever (FMF) patients and ...
Karatay, Saliha, UZKESER, Hülya, Erdem, Fazile Hatipoglu, ERDAL, Akın, Yanmaz, Vefa, YILDIRIM, Kadir   +5 more
core   +1 more source