Results 71 to 80 of about 159,782 (296)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Classification of Certain Cyclic LCD Codes

Scientific Annals of Computer Science
We show that a necessary and sufficient condition for a cyclic code C of length N over a finite chain ring R (whose maximal ideal has nilpotence 2) to be an LCD code is that C = (f(x)), where f(X) is a self-reciprocal monic divisor of X^N − 1 in R[X] and
Seth Gannon, Hamid Kulosman
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Various structures of cyclic codes and LCD codes over $ GR(p^3, m)[v]/\langle v^2-p^2\alpha, p v\rangle $

AIMS Mathematics
Let $ p $ be a prime and $ m $ a positive integer. This paper investigates cyclic and self-dual codes of length $ n $ over the local Frobenius non-chain ring $ R = \mathrm{GR}(p^3, m)[v] $, with $ v^2 = p^2 \alpha $, $ \alpha \in \mathbb{F}^*_{p^m ...
Sami Alabiad, Alhanouf Ali Alhomaidhi
doaj   +1 more source

The Permutation Groups and the Equivalence of Cyclic and Quasi-Cyclic Codes [PDF]

, 2010
We give the class of finite groups which arise as the permutation groups of cyclic codes over finite fields. Furthermore, we extend the results of Brand and Huffman et al. and we find the properties of the set of permutations by which two cyclic codes of
Guenda, Kenza
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Design of LDPC Codes: A Survey and New Results

Journal of Communications Software and Systems, 2006
This survey paper provides fundamentals in the design of LDPC codes. To provide a target for the code designer, we first summarize the EXIT chart technique for determining(near-)optimal degree distributions for LDPC code ensembles.
Gianluigi Liva, Shumei Song, Lan Lan, Yifei Zhang, Shu Lin, William E. Ryan   +5 more
doaj  

On Double Cyclic Codes and Applications to DNA Codes

Mathematics
In this paper, we investigate the structure of double cyclic codes of length (α,β) over R=F4+ϱF4,ϱ2=0 and give a minimal spanning set of double cyclic codes. Moreover, we extend this study to construct DNA codes from R-double cyclic codes.
Amal S. Alali, Mohd Anwar, Muzibur Rahman Mozumder   +2 more
doaj   +1 more source

Transform Domain Characterization of Dual Group Codes of Cyclic Group Codes over Elementary Abelian Groups

Sultan Qaboos University Journal for Science, 2009
The group of characters of an elementary Abelian group  has been used to define duality between its subgroups, which in turn is extended to duality between group codes.
Adnan Abdulla Zain
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source