Results 101 to 110 of about 20,307 (290)

Stability of string configurations dual to quarkonium states in AdS/CFT

, 2007
We extend our earlier work, regarding the perturbative stability of string configurations used for computing the interaction potential of heavy quarks within the gauge/gravity correspondence, to cover a more general class of gravity duals.
Aharony, Ahn, Ahn, Arfken, Argyres, Avramis, Avramis, Avramis, Avramis, Bakas, Bakas, Berenstein, Bliss, Brandhuber, Brandhuber, Brandhuber, Cai, Callan, Callen, Caratheodory, Chernicoff, Courant, Cvetic, Cvetic, Cvetic, Cáceres, Durand, Freedman, Friess, Frolov, Frolov, Gross, Gubser, Gubser, Harmark, Hernández, Hernández, Ince, Kinar, Kinar, Klebanov, Klebanov, Klebanov, Konstadinos Sfetsos, Konstadinos Siampos, Kraus, Landau, Leigh, Liu, Liu, Lunin, Maldacena, Maldacena, Maldacena, Natsuume, Peeters, Rashkov, Rey, Rey, Russo, Sfetsos, Sonnenschein, Spyros D. Avramis, Whittaker, Witten, Witten   +65 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Effects of grain size distribution on the initial strain shear modulus of calcareous sand [PDF]

, 2015
The soil’s small strain shear modulus, Gmax or G0, is applied in dynamic behavior analyses and is correlated to other soil properties (density and void ratio) for predicting soil dynamic behavior under seismic loadings such as earthquakes, machinery or ...
Haegeman, Wim, Mengé, P, Pham, Huu Ha Giang, Van Impe, PO, Van Impe, William   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Triaxial compressive failure of thermally damaged granite following low- and high-cycle fatigue loading

Results in Engineering
This paper investigated the triaxial compressive characteristics of thermally damaged granite following cyclic loading. Thermal treatments at various high temperatures (200.0 °C, 400.0 °C, 500.0 °C, and 600.0 °C) were performed on granite.
B. Qiu, Z. Wang, X. Zhao, L.F. Fan
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A simple permanent deformation model of rockfill materials

Water Science and Engineering, 2018
Existing experimental results have shown that using a semi-log linear relationship between the permanent volumetric strain and cyclic number underestimates the volumetric deformation of rockfill materials with a large cyclic number, and that the error ...
De-gao Zou, Jing-mao Liu, Xian-jing Kong, Chen-guang Zhou, Qing-po Yang   +4 more
doaj   +1 more source

Theoretical studies on the mechanical behavior of granular materials under very low intergranular stresses [PDF]

The salient aspects of the theoretical modeling of a conventional triaxial test (CTC) of a cohesionless granular medium with stress and strain rate loading are described.
French, Kenneth W., Jr.
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source