Results 151 to 160 of about 1,609,424 (285)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Effect of Partial Silica Replacement with Carbon Black, Graphene, and Carbon Nanotubes on the Fatigue Performance and Ageing Behaviour of SBR Compounds. [PDF]

Materials (Basel)
Gozdek T, Sadurska J, Klajn K, Bieliński DM.   +3 more
europepmc   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Sortase-mediated generation of various macrocyclic peptide scaffolds from low-reactivity electrophilic substrates. [PDF]

Chem Sci
Xia ZM, Wei HM, Xue JH, Sun YN, Wan XC, Tong HR, Zhou L, Shi P, Fang GM, Tian C.   +9 more
europepmc   +1 more source

Numerical Framework for Modeling Cyclic Degradation of Soils

, 2017
For many years fatigue in soils has been a major design challenge. Due to cyclic loading the material behavior changes and permanent deformations are observed. Although explicit cyclic calculation methods exists, none are ideal for cyclic design computation. The available methods are currently either to simplified, labor-intensive or inaccurate.
openaire   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

A Unified Damage-Plasticity Constitutive Framework for Freeze-Thaw-Damaged Concrete Under Monotonic and Cyclic Compression. [PDF]

Materials (Basel)
Gao P, Zhao W, Xie J, Du X, Pan Y, Chang L.   +5 more
europepmc   +1 more source

Low‐Temperature Imidization of Polyimides (PI) for Scalable Manufacturing of Flexible Wearable Electronics

Advanced Engineering Materials, EarlyView.
Low‐temperature imidization of PEG‐modified polyimide enables fully screen‐printed, roll‐to‐roll fabrication of flexible electrodes on PET substrates, delivering robust mechanical durability and reliable ECG/EMG signal performance for wearable electronics.
Akib Abdullah Khan, Jong‐Hoon Kim
wiley   +1 more source

An interpretable learning framework for exploring superelastic degradation of NiTi shape memory alloys using multimodal data. [PDF]

Nat Commun
Hu Y, Wang H, Chen M, Chen G, Wang C, Guo B, Fu MW.   +6 more
europepmc   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

Advanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares, Nadège Bouchonneau, Christian Jochum, Donald Radford   +3 more
wiley   +1 more source