Results 1 to 10 of about 3,359,188 (286)

Pentacarbonyl(imidazolidine-2-thione-κS)tungsten(0)

Acta Crystallographica Section E, 2010
In the title complex, [W(C3H6N2S)(CO)5], the W atom displays an octahedral coordination with five CO molecules and an imidazolidine-2-thione molecule. The W(CO)5 unit is coordinated by the cyclic thione ligand through a W—S dative bond.
Salah Merniz, Mahiedine Mokhtari, Hénia Mousser, Lahcène Ouahab, Abdelhamid Mousser   +4 more
doaj   +2 more sources

Cyclic AMP Pathway Activation and Extracellular Zinc Induce Rapid Intracellular Zinc Mobilization in Candida albicans

Frontiers in Microbiology, 2018
Zinc is an essential micronutrient, required for a range of zinc-dependent enzymes and transcription factors. In mammalian cells, zinc serves as a second messenger molecule. However, a role for zinc in signaling has not yet been established in the fungal
Lasse Kjellerup, Lasse Kjellerup, Anne-Marie L. Winther, Duncan Wilson, Anja T. Fuglsang   +4 more
doaj   +1 more source

4-Carbamoylpiperidinium acetate monohydrate

Acta Crystallographica Section E, 2010
In the structure of the title compound, C6H13N2O+·C2H3O2−·H2O, the amide H atoms of the cations form centrosymmetric cyclic hydrogen-bonding associations incorporating two water molecules [graph set R42(8)], which are conjoint
Urs D. Wermuth, Graham Smith
doaj   +1 more source

Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides

Journal of Oral Microbiology, 2019
Background: Cyclic dinucleotides (cyclic di-guanosine monophosphate (c-di-GMP) and cyclic di-adenosine monophosphate (c-di-AMP)) and lipopolysaccharides (LPS) are pathogen-associated molecular patterns (PAMPs).
Samira Elmanfi, Jie Zhou, Herman O. Sintim, Eija Könönen, Mervi Gürsoy, Ulvi Kahraman Gürsoy   +5 more
doaj   +1 more source

6-Bromo-2-methylsulfanyl-1,3-benzothiazole

Acta Crystallographica Section E, 2011
The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS ...
Michał A. Dobrowolski, Marta Struga, Daniel Szulczyk   +2 more
doaj   +1 more source

ABCD of the phosphodiesterase family: interaction and differential activity in COPD

International Journal of COPD, 2008
David MG HalpinRoyal Devon and Exeter Hospital, Exeter, EX2 5DW, UKAbstract: Phosphodiesterases (PDEs) are important enzymes that hydrolyze the cyclic nucleotides adenosine 3′5′-cyclic monophosphate (cAMP) and guanosine 3′5 ...
David MG Halpin
doaj  

The Emerging Role of Phosphodiesterase Inhibitors in Fragile X Syndrome and Autism Spectrum Disorder

Pharmaceuticals
Autism spectrum disorder (ASD) and Fragile X syndrome (FXS) are neurodevelopmental disorders marked by deficits in communication and social interaction, often accompanied by anxiety, seizures, and intellectual disability.
Shilu Deepa Thomas, Hend Abdulaziz Mohammed, Mohammad I. K. Hamad, Murat Oz, Yauhen Statsenko, Bassem Sadek   +5 more
doaj   +1 more source

Cyclic AMP but Not Calmodulin as a Potential Wasoconstrictor in Simulated Reperfusion. [PDF]

Int J Mol Sci, 2023
Ohla J, Wiciński M, Słupski M, Zabrzyński J, Malinowski B.   +4 more
europepmc   +1 more source

Membrane-embedded CdaA is required for efficient synthesis of second messenger cyclic di-AMP

Communications Biology
Cyclic di-adenylate monophosphate (cyclic di-AMP) is an important second messenger in microorganisms. Cyclic di-AMP regulates bacterial cell volume and turgor via control of potassium and compatible solute transport but is also involved in many other ...
Alexander J. Foster, Haoyang Li, Panagiotis Drougkas, Gea. K. Schuurman-Wolters, Joeri ten Kate, Cristina Paulino, Bert Poolman   +6 more
doaj   +1 more source

Genome-wide screening reveals metabolic regulation of stop-codon readthrough by cyclic AMP. [PDF]

Nucleic Acids Res, 2023
Lyu Z, Villanueva P, O'Malley L, Murphy P, Augenstreich J, Briken V, Singh A, Ling J.   +7 more
europepmc   +1 more source