Results 31 to 40 of about 131,836 (300)

Relationship between cyclic AMP production and lipolysis induced by forskolin in rat fat cells.

open access: yesJournal of Lipid Research, 1992
Forskolin (7 beta-acetoxy-8, 13-epoxy-1 alpha,6 beta,9 alpha-trihydroxy-labd-14-ene-11-one) induced both cyclic AMP production and lipolysis in intact fat cells, but stimulated lipolysis without increasing cyclic AMP at a concentration of 10(-5) M ...
H Okuda, C Morimoto, T Tsujita
doaj   +1 more source

Cyclic AMP increases COX-2 expression via mitogen-activated kinase in human myometrial cells [PDF]

open access: yes, 2011
Cyclic AMP (cAMP) is the archetypal smooth muscle relaxant, mediating the effects of many hormones and drugs. However, recently PGI2, acting via cAMP/PKA, was found to increase contraction-associated protein expression in myometrial cells and to promote ...
Mandeep Kandola   +20 more
core   +1 more source

Evolution of size and pattern in the social amoebas [PDF]

open access: yes, 2007
A fundamental goal of biology is to understand how novel phenotypes evolved through changes in existing genes. The Dictyostelia or social amoebas represent a simple form of multicellularity, where starving cells aggregate to build fruiting structures ...
Schaap, P.; id_orcid
core   +1 more source

Activation of hormone-sensitive lipase in extracts of adipose tissue

open access: yesJournal of Lipid Research, 1970
Rat adipose tissue was homogenized in 0.154 m KCI, and the supernatant fluid, obtained after centrifugation at 15,000 g, was extracted with benzene to remove triglycerides. Most of the lipase activity in the extracted fluid was precipitated with ammonium
SU-CHEN TSAI   +2 more
doaj   +1 more source

Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin [PDF]

open access: yes, 2016
FIC domain proteins mediate post-translational modifications of target proteins, which typically results in their inactivation. Depending on the conservation of crucial active site residues, the FIC fold serves as structural scaffold for various ...
Stanger, Frédéric V.   +11 more
core   +1 more source

Ultrasonic controllable synthesis of sulfur-functionalized metal–organic frameworks (S-MOFs) and their application in piezo-photocatalytic rapid reduction of hexavalent chromium (Cr)

open access: yesUltrasonics Sonochemistry
The United Nations’ Sustainable Development Goals (SDGs) are significant in guiding modern scientific research. In recent years, scholars have paid much attention to MOFs materials as green materials.
Zhiwei Liu   +8 more
doaj   +1 more source

Cyclic AMP in prokaryotes

open access: yesMicrobiological Reviews, 1992
Cyclic AMP (cAMP) is found in a variety of prokaryotes including both eubacteria and archaebacteria. cAMP plays a role in regulating gene expression, not only for the classic inducible catabolic operons, but also for other categories. In the enteric coliforms, the effects of cAMP on gene expression are mediated through its interaction with and ...
J L, Botsford, J G, Harman
openaire   +2 more sources

The Role of Cyclic AMP Signaling in Cardiac Fibrosis

open access: yesCells, 2019
Myocardial stress and injury invariably promote remodeling of the cardiac tissue, which is associated with cardiomyocyte death and development of fibrosis. The fibrotic process is initially triggered by the differentiation of resident cardiac fibroblasts
Marion Delaunay   +3 more
doaj   +1 more source

Cyclic AMP signalling in pancreatic islets

open access: yes, 2010
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Nigel J. Pyne   +7 more
core   +1 more source

Activation of STING Based on Its Structural Features

open access: yesFrontiers in Immunology, 2022
The cGAS-cGAMP-STING pathway is an important innate immune signaling cascade responsible for the sensing of abnormal cytosolic double-stranded DNA (dsDNA), which is a hallmark of infection or cancers.
Behzad Hussain   +8 more
doaj   +1 more source

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