Results 31 to 40 of about 1,146,764 (346)

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

open access: yesNature Communications, 2016
Biguanides such as metformin have previously been shown to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP) signalling independently of AMP-activated protein kinase (AMPK) via direct inhibition of adenylate cyclase by AMP.
M. Johanns   +16 more
semanticscholar   +1 more source

Cyclic AMP metabolism in adipose tissue of exercise-trained rats.

open access: yesJournal of Lipid Research, 1978
Cyclic AMP metabolism in epididymal adipose tissue of exercise-trained rats was examined to determine if training induced changes in cyclic AMP production or inactivation.
E W Askew   +3 more
doaj   +1 more source

The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets

open access: yesCells, 2020
The cell cycle is controlled by microtubule-associated serine/threonine kinase-like (MASTL), which phosphorylates the cAMP-regulated phosphoproteins 19 (ARPP19) at S62 and 19e/α-endosulfine (ENSA) at S67and converts them into protein phosphatase 2A (
Elena J. Kumm   +6 more
doaj   +1 more source

Non-Enzymatic Oligomerization of 3', 5' Cyclic AMP. [PDF]

open access: yesPLoS ONE, 2016
Recent studies illustrate that short oligonucleotide sequences can be easily produced from nucleotide precursors in a template-free non-enzymatic way under dehydrating conditions, i.e. using essentially dry materials. Here we report that 3',5' cyclic AMP
Giovanna Costanzo   +8 more
doaj   +1 more source

The role of cyclic nucleotide on fetal and neonantal erythropoiesis [PDF]

open access: yes, 1974
For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core   +1 more source

Copper Regulates Cyclic AMP-Dependent Lipolysis

open access: yesNature Chemical Biology, 2016
Cell signaling relies extensively on dynamic pools of redox-inactive metal ions such as sodium, potassium, calcium, and zinc, but their redox-active transition metal counterparts such as copper and iron have been studied primarily as static enzyme ...
Lakshmi Krishnamoorthy   +15 more
semanticscholar   +1 more source

Cyclic Amp And Psoriasis

open access: yesJournal of Investigative Dermatology, 1975
Evidence that an adenyl cyclase system is present in all mammalian epidermis is reviewed. This adenyl cyclase is stimulated by at least two separate types of chemicals: catecholamines, which act at a beta-adrenergic receptor site, and prostaglandins of the E series, which act at a separate site.
Halprin, Kenneth M   +5 more
openaire   +2 more sources

Digital image processing of optical density wave propagation in Dictyostelium discoideum and analysis of the effects of caffeine and ammonia [PDF]

open access: yes, 1989
Waves of chemotactic movement during the early phase of aggregation in Dictyostelium discoideum were analyzed by digital image processing in a manner that immediately shows the following parameters: wave propagation velocity, period length, wave ...
Siegert, Florian, Weijer, Cornelis J.
core   +1 more source

Relationship between cyclic AMP production and lipolysis induced by forskolin in rat fat cells.

open access: yesJournal of Lipid Research, 1992
Forskolin (7 beta-acetoxy-8, 13-epoxy-1 alpha,6 beta,9 alpha-trihydroxy-labd-14-ene-11-one) induced both cyclic AMP production and lipolysis in intact fat cells, but stimulated lipolysis without increasing cyclic AMP at a concentration of 10(-5) M ...
H Okuda, C Morimoto, T Tsujita
doaj   +1 more source

RAS and beyond: the many faces of the neurofibromatosis type 1 protein

open access: yesDisease Models & Mechanisms, 2022
Neurofibromatosis type 1 is a rare neurogenetic syndrome, characterized by pigmentary abnormalities, learning and social deficits, and a predisposition for benign and malignant tumor formation caused by germline mutations in the NF1 gene.
Corina Anastasaki   +2 more
doaj   +1 more source

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