Results 51 to 60 of about 142,987 (309)

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

An experimental study of anisotropic fatigue behavior of rolled AZ31B magnesium alloy

Materials & Design, 2020
Material orientation effects on cyclic deformation and fatigue of a rolled AZ31B magnesium (Mg) alloy were experimentally studied. Monotonic tension, monotonic compression, and fully reversed strain-controlled tension-compression experiments were ...
Yuqian Wang, Duke Culbertson, Yanyao Jiang   +2 more
doaj   +1 more source

Fatigue effect in ferroelectric crystals: Growth of the frozen domains [PDF]

, 2012
The model of the fatigue effect during cyclic switching caused by growth of the frozen domain area with charged domain walls has been proposed. It was claimed on the basis of the previous experimental results that for switching in increasing field the ...
Akhmatkhanov, A. R., Baturin, I. S., Shur, V. Ya., Шур, В. Я.   +3 more
core   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Molecular Dynamics Simulation of Low-Cycle Fatigue Behavior of Single/Polycrystalline Iron

Nanomaterials
The fatigue plastic mechanism and dislocation characteristics of engineering materials are the key to studying fatigue damage. In this study, the molecular dynamics (MD) method was employed to investigate the microstructural characteristics and fatigue ...
Tianyu Zhang, Jinjie Zhou, Jinchuan Shen
doaj   +1 more source

Fatigue Performance of SFPSC under Hot-Wet Environments and Cyclic Bending Loads

Advances in Materials Science and Engineering, 2018
A new structural material named “steel fiber polymer structural concrete (SFPSC)” with features of both high strength and high toughness was developed by this research group and applied to the bridge superstructures in the hot-wet environments.
Shanshan Luo, Peiyan Huang, Xinyan Guo, Xiaohong Zheng   +3 more
doaj   +1 more source

A New Approach to Estimate the Fatigue Limit of Steels Based on Conventional and Cyclic Indentation Testing

Metals, 2022
For a reliable design of structural components, valid information about the fatigue strength of the material used is a prerequisite. As the determination of the fatigue properties, and especially the fatigue limit σw, requires a high experimental effort,
David Görzen, Pascal Ostermayer, Patrick Lehner, Bastian Blinn, Dietmar Eifler, Tilmann Beck   +5 more
doaj   +1 more source

Linear matching method on the evaluation of cyclic behaviour with creep effect [PDF]

, 2012
This paper describes a new Linear Matching Method (LMM) technique for the direct evaluation of cyclic behaviour with creep effects of structures subjected to a general load condition in the steady cyclic state.
Chen, Haofeng, Chen, Weihang, Ure, James Michael   +2 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source