Results 71 to 80 of about 949,461 (274)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Automorphisms of Regular Wreath Product 𝑝-Groups

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2009
We present a useful new characterization of the automorphisms of the regular wreath product group 𝑃 of a finite cyclic 𝑝-group by a finite cyclic 𝑝-group, for any prime 𝑝, and we discuss an application.
Jeffrey M. Riedl
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nonlinear, nonbinary cyclic group codes [PDF]

open access: yes
New cyclic group codes of length 2(exp m) - 1 over (m - j)-bit symbols are introduced. These codes can be systematically encoded and decoded algebraically.
Solomon, G.
core   +1 more source

Cyclic homology and group actions [PDF]

open access: yesJournal of Geometry and Physics, 2018
v2: final version. To appear in J. Geom. Phys.
openaire   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Digraph Groups Without Leaf Having An Arc Count One Greater Than Their Vertex

open access: yesCumhuriyet Science Journal
This paper investigates a particular class of digraph groups that are defined by non-empty balanced presentations. Each relation is expressed in the form R(x,y), where x and y are distinct generators, and R(⋅,⋅) is based on a fixed cyclically reduced ...
Mehmet Sefa Cihan
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

CYCLIC SUBGROUPS IN THE CHARACTER GROUP

open access: yesВестник Кемеровского государственного университета, 2015
V. V. Chueshev began building the general theory of multiplicative functions and Prym differentials on compact Riemann surfaces for arbitrary characters.
M. I. Tulina, О. А. Chuesheva
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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